| Reaction Details |
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 | Report a problem with these data |
| Target | Oxidized purine nucleoside triphosphate hydrolase |
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| Ligand | BDBM50210165 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1634434 (CHEMBL3877226) |
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| IC50 | 100±n/a nM |
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| Citation |  Munoz, L Non-kinase targets of protein kinase inhibitors. Nat Rev Drug Discov16:424-440 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Oxidized purine nucleoside triphosphate hydrolase |
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| Name: | Oxidized purine nucleoside triphosphate hydrolase |
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| Synonyms: | 2-hydroxy-dATP diphosphatase | 3.6.1.- | 3.6.1.56 | 7,8-dihydro-8-oxoguanine triphosphatase | 8-oxo-dGTPase | 8ODP_HUMAN | MTH1 | Methylated purine nucleoside triphosphate hydrolase | MutT homolog 1 protein (MTH1) | NUDT1 | Nucleoside diphosphate-linked moiety X motif 1 | Nudix motif 1 | Oxidized purine nucleoside triphosphate hydrolase [42-197] |
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| Type: | Protein |
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| Mol. Mass.: | 22514.81 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P36639 |
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| Residue: | 156 |
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| Sequence: | MGASRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGARRELQEESGLT
VDALHKVGQIVFEFVGEPELMDVHVFCTDSIQGTPVESDEMRPCWFQLDQIPFKDMWPDD
SYWFPLLLQKKKFHGYFKFQGQDTILDYTLREVDTV
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| BDBM50210165 |
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| n/a |
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| Name | BDBM50210165 |
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| Synonyms: | CHEMBL1709874 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H14N6 |
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| Mol. Mass. | 254.2905 |
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| SMILES | Nc1nc(NCCc2ccccc2)c2nc[nH]c2n1 |
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| Structure | 
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