| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase TEM |
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| Ligand | BDBM50212644 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_40709 (CHEMBL655783) |
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| IC50 | 15.3±n/a nM |
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| Citation |  TBA Bioorg Med Chem Lett3:2247-2252 (1993) |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-lactamase TEM |
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| Name: | Beta-lactamase TEM |
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| Synonyms: | BLAT_ECOLX | Bacterial beta-lactamase TEM | Beta-lactamase (TEM-1) | Beta-lactamase TEM | Beta-lactamase TEM-1 | Beta-lactamase TEM-1b | Beta-lactamase TEM1D | Beta-lactamase TEM1E | Beta-lactamase TEM1F | TEM beta lactamase | TEM extended-spectrum beta-lactamase | TEM-1 beta-lactamase | bla |
|---|
| Type: | Enzyme |
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| Mol. Mass.: | 31512.33 |
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| Organism: | Escherichia coli |
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| Description: | P62593 |
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| Residue: | 286 |
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| Sequence: | MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGYIELDLNSGKILESFRP
EERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVREL
CSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTM
PAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGS
RGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
|
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|
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| BDBM50212644 |
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| n/a |
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| Name | BDBM50212644 |
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| Synonyms: | CHEMBL73450 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H14BrN3O3S2 |
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| Mol. Mass. | 392.292 |
|---|
| SMILES | [H][C@]12S[C@@](C)(CSc3nccn3C)[C@@H](N1C(=O)[C@H]2Br)C(O)=O |
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| Structure | 
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