| Reaction Details |
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 | Report a problem with these data |
| Target | Neutrophil elastase |
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| Ligand | BDBM50212647 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_63970 (CHEMBL677438) |
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| KON | 5.600000 M-1s-1 |
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| Citation |  TBA Bioorg Med Chem Lett3:2295-2298 (1993) |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Neutrophil elastase |
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| Name: | Neutrophil elastase |
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| Synonyms: | Bone marrow serine protease | Chymotrypsin | Coagulation factor X | ELA2 | ELANE | ELNE_HUMAN | Elastase | Elastase-2 | HLE | Human leukocyte elastase | Leukocyte elastase | Leukocyte elastase (HLE) | Medullasin | Neutrophil elastase | Neutrophil elastase (HNE) | Neutrophil elastase (NE) | PMN elastase | Thrombin | Trypsin |
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| Type: | Enzyme |
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| Mol. Mass.: | 28532.38 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P08246 |
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| Residue: | 267 |
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| Sequence: | MTLGRRLACLFLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGGHFCGATLI
APNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVI
LQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSL
CRRSNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVN
WIDSIIQRSEDNPCPHPRDPDPASRTH
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| BDBM50212647 |
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| n/a |
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| Name | BDBM50212647 |
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| Synonyms: | CHEMBL75236 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H20N2O5 |
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| Mol. Mass. | 368.3832 |
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| SMILES | CC[C@@H]1[C@H](Oc2ccc(cc2)C(O)=O)N(C(=O)NCc2ccccc2)C1=O |
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| Structure | 
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