| Reaction Details |
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 | Report a problem with these data |
| Target | Vasopressin V1a/V1b receptor |
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| Ligand | BDBM50212860 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_214393 (CHEMBL819414) |
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| IC50 | 600±n/a nM |
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| Citation |  TBA Bioorg Med Chem Lett3:1633-1636 (1993) |
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| More Info.: | Get all data from this article, Assay Method |
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| Vasopressin V1a/V1b receptor |
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| Name: | Vasopressin V1a/V1b receptor |
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| Synonyms: | Vasopressin V1 receptor |
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| Type: | n/a |
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| Mol. Mass.: | n/a |
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| Description: | ASSAY_ID of ChEMBL is 329920 |
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| Components: | This complex has 2 components. |
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| Component 1 |
| Name: | Vasopressin V1a receptor |
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| Synonyms: | AVPR V1a | AVPR1 | AVPR1A | Antidiuretic hormone receptor 1a | V1AR_HUMAN | V1aR | VASOPRESSIN V1A | Vascular/hepatic-type arginine vasopressin receptor | Vasopressin V1 receptor | Vasopressin V1a receptor | Vasopressin receptor |
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| Type: | Receptor |
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| Mol. Mass.: | 46820.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P37288 |
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| Residue: | 418 |
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| Sequence: | MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAV
TFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGP
DWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFV
LSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFIC
YNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAY
IVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCV
QSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST
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| Component 2 |
| Name: | Vasopressin V1b receptor |
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| Synonyms: | AVPR V1b | AVPR V3 | AVPR1B | AVPR3 | Antidiuretic hormone receptor 1b | V1BR_HUMAN | V1bR | VASOPRESSIN V1B | VPR3 | Vasopressin V1b receptor | Vasopressin V1b receptor (V1b) | Vasopressin V3 | Vasopressin V3 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 46985.01 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P47901 |
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| Residue: | 424 |
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| Sequence: | MDSGPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVLVLATGGNLAVLLTLG
QLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMFA
STYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQG
SGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQAWRVG
GGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAPFFSV
QMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRHLACCGGPQ
PRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSGRPRPEESPRDLELADGEGTAE
TIIF
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| BDBM50212860 |
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| n/a |
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| Name | BDBM50212860 |
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| Synonyms: | CHEMBL42432 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H31N3O5 |
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| Mol. Mass. | 465.5414 |
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| SMILES | CC(=O)NC(O)CCOc1ccc(cc1)C(=O)N1CCC(CC1)N1C(=O)CCc2ccccc12 |
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| Structure | 
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