| Reaction Details |
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 | Report a problem with these data |
| Target | PBP2A |
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| Ligand | BDBM50213266 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_153662 (CHEMBL757854) |
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| IC50 | 4.28e+05±n/a nM |
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| Citation |  TBA Bioorg Med Chem Lett5:1427-1432 (1995) |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| PBP2A |
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| Name: | PBP2A |
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| Synonyms: | MecA PBP2' (penicillin binding protein 2') | PBP2A | Penicillin-binding protein | mecA |
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| Type: | PROTEIN |
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| Mol. Mass.: | 76283.66 |
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| Organism: | Staphylococcus aureus |
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| Description: | ChEMBL_105733 |
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| Residue: | 668 |
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| Sequence: | MKKIKIVPLILIVVVVGFGIYFYASKDKEINNTIDAIEDKNFKQVYKDSSYISKSDNGEV
EMTERPIKIYNSLGVKDINIQDRKIKKVSKNKKRVDAQYKIKTNYGNIDRNVQFNFVKED
GMWKLDWDHSVIIPGMQKDQSIHIENLKSERGKILDRNNVELANTGTHMRLGIVPKNVSK
KDYKAIAKELSISEDYINNKWIKIGYKMIPSFHFKTVKKMDEYLSDFAKKFHLTTNETES
RNYPLEKATSHLLGYVGPINSEELKQKEYKGYKDDAVIGKKGLEKLYDKKLQHEDGYRVT
IVDDNSNTIAHTLIEKKKKDGKDIQLTIDAKVQKSIYNNMKNDYGSGTAIHPQTGELLAL
VSTPSYDVYPFMYGMSNEEYNKLTEDKKEPLLNKFQITTSPGSTQKILTAMIGLNNKTLD
DKTSYKIDGKGWQKDKSWGGYNVTRYEVVNGNIDLKQAIESSDNIFFARVALELGSKKFE
KGMKKLGVGEDIPSDYPFYNAQISNKNLDNEILLADSGYGQGEILINPVQILSIYSALEN
NGNINAPHLLKDTKNKVWKKNIISKENINLLNDGMQQVVNKTHKEDIYRSYANLIGKSGT
AELKMKQGESGRQIGWFISYDKDNPNMMMAINVKDVQDKGMASYNAKISGKVYDELYENG
NKKYDIDE
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|
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| BDBM50213266 |
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| n/a |
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| Name | BDBM50213266 |
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| Synonyms: | CHEBI:471744 | Imipenem | MK-0787 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H17N3O4S |
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| Mol. Mass. | 299.346 |
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| SMILES | [H][C@]12CC(SCCNC=N)=C(N1C(=O)[C@]2([H])[C@@H](C)O)C(O)=O |r,c:9| |
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| Structure | 
|
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