| Reaction Details |
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 | Report a problem with these data |
| Target | Similar to alpha-tubulin isoform 1 |
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| Ligand | BDBM50014846 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_225817 (CHEMBL844433) |
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| IC50 | 8700±n/a nM |
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| Citation |  Miller, TA; Bulman, AL; Thompson, CD; Macdonald, TL The synthesis and evaluation of temperature sensitive tubulin toxins. Bioorg Med Chem Lett9:407-12 (1999) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Similar to alpha-tubulin isoform 1 |
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| Name: | Similar to alpha-tubulin isoform 1 |
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| Synonyms: | Similar to alpha-tubulin isoform 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 10383.05 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_104716 |
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| Residue: | 99 |
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| Sequence: | CVSASPSTLARLVSRSAMPAGSSTAWNTAFSPMARCQVTKTIGGGDDSFNTFFSETGAGK
HVPRAVFVDLEPTVIDEVRTGTYRSSSTLSSSSQAKKMP
|
|
|
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| BDBM50014846 |
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| n/a |
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| Name | BDBM50014846 |
|---|
| Synonyms: | (S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamide | (S)-colchicine | 7alphaH-colchicine | CHEMBL107 | COLCHICINE | N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide | colchicina | colchicinum |
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| Type | Small organic molecule |
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| Emp. Form. | C22H25NO6 |
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| Mol. Mass. | 399.437 |
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| SMILES | COc1cc2CC[C@H](NC(C)=O)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC |r| |
|---|
| Structure | 
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