| Reaction Details |
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 | Report a problem with these data |
| Target | Putative penicillin-binding protein 2B |
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| Ligand | BDBM50218760 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_153519 (CHEMBL764472) |
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| IC50 | >703000±n/a nM |
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| Citation |  Chen, Z; Demuth, TP; Wireko, FC Stereoselective synthesis and antibacterial evaluation of 4-amido-isothiazolidinone oxides. Bioorg Med Chem Lett11:2111-5 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Putative penicillin-binding protein 2B |
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| Name: | Putative penicillin-binding protein 2B |
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| Synonyms: | B9Z04_05970 | B9Z08_04335 | Cell division protein FtsI (Peptidoglycan synthetase) | EP54_05770 | EQ90_05620 | ERS072738_01739 | HMPREF3211_00860 | Penicillin-binding protein | Penicillin-binding protein 1 | Putative penicillin-binding protein 2B | Synonyms=ftsI_2 | pbp1 | pbpA |
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| Type: | PROTEIN |
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| Mol. Mass.: | 82733.22 |
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| Organism: | Staphylococcus aureus |
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| Description: | ChEMBL_105733 |
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| Residue: | 744 |
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| Sequence: | MAKQKIKIKKNKIGAVLLVGLFGLLFFILVLRISYIMITGHSNGQDLVMKANEKYLVKNA
QQPERGKIYDRNGKVLAEDVERYKLVAVIDKKASANSKKPRHVVDKKETAKKLSTVINMK
PEEIEKRLSQKKAFQIEFGRKGTNLTYQDKLKIEKMNLPGISLLPETERFYPNGNFASHL
IGRAQKNPDTGELKGALGVEKIFDSYLSGSKGSLRYIHDIWGYIAPNTKKEKQPKRGDDV
HLTIDSNIQVFVEEALDGMVERYQPKDLFAVVMDAKTGEILAYSQRPTFNPETGKDFGKK
WANDLYQNTYEPGSTFKSYGLAAAIQEGAFDPDKKYKSGHRDIMGSRISDWNRVGWGEIP
MSLGFTYSSNTLMMHLQDLVGADKMKSWYERFGFGKSTKGMFDGEAPGQIGWSNELQQKT
SSFGQSTTVTPVQMLQAQSAFFNDGNMLKPWFVNSVENPVSKRQFYKGQKQIAGKPITKD
TAEKVEKQLDLVVNSKKSHAANYRIDGYEVEGKTGTAQVAAPNGGGYVKGPNPYFVSFMG
DAPKKNPKVIVYAGMSLAQKNDQEAYELGVSKAFKPIMENTLKYLNVGKSKDDTSNAEYS
KVPDVEGQDKQKAIDNVSAKSLEPVTIGSGTQIKAQSIKAGNKVLPHSKVLLLTDGDLTM
PDMSGWTKEDVIAFENLTNIKVNLKGSGFVSHQSISKGQKLTEKDKIDVEFSSENVDSNS
TNNSDSNSDDKKKSDSKTDKDKSD
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| BDBM50218760 |
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| n/a |
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| Name | BDBM50218760 |
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| Synonyms: | CHEMBL304750 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H21N3O5S |
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| Mol. Mass. | 355.409 |
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| SMILES | CCCCNOS(=O)(=O)N1C[C@H](NC(=O)Cc2ccccc2)C1=O |
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| Structure | 
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