| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1F |
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| Ligand | BDBM28583 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2096 (CHEMBL617132) |
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| Ki | <1000±n/a nM |
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| Citation |  Bromidge, SM; Clarke, SE; King, FD; Lovell, PJ; Newman, H; Riley, G; Routledge, C; Serafinowska, HT; Smith, DR; Thomas, DR Bicyclic piperazinylbenzenesulphonamides are potent and selective 5-HT6 receptor antagonists. Bioorg Med Chem Lett12:1357-60 (2002) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 1F |
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| Name: | 5-hydroxytryptamine receptor 1F |
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| Synonyms: | 5-HT-1F | 5-HT1F | 5-hydroxytryptamine receptor 1F | 5HT1F_HUMAN | HTR1EL | HTR1F | Serotonin (5-HT) receptor | Serotonin 1f (5-HT1f) receptor | Serotonin receptor 1F |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41724.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | 5-HT1F HTR1F HUMAN::P30939 |
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| Residue: | 366 |
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| Sequence: | MDFLNSSDQNLTSEELLNRMPSKILVSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANY
LICSLAVTDFLVAVLVMPFSIVYIVRESWIMGQVVCDIWLSVDITCCTCSILHLSAIALD
RYRAITDAVEYARKRTPKHAGIMITIVWIISVFISMPPLFWRHQGTSRDDECIIKHDHIV
STIYSTFGAFYIPLALILILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLLESGEKSTKS
VSTSYVLEKSLSDPSTDFDKIHSTVRSLRSEFKHEKSWRRQKISGTRERKAATTLGLILG
AFVICWLPFFVKELVVNVCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQK
LVRCRC
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| BDBM28583 |
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| n/a |
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| Name | BDBM28583 |
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| Synonyms: | 5-chloro-N-[4-methoxy-3-(piperazin-1-yl)phenyl]-3-methyl-1-benzothiophene-2-sulfonamide hydrochloride | CHEMBL431298 | SB 271046 | SB-271046 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H22ClN3O3S2 |
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| Mol. Mass. | 451.99 |
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| SMILES | COc1ccc(NS(=O)(=O)c2sc3ccc(Cl)cc3c2C)cc1N1CCNCC1 |
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| Structure | 
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