| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 4 |
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| Ligand | BDBM50079052 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_45434 (CHEMBL657034) |
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| Ki | 48.0±n/a nM |
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| Citation |  Agrawal, VK; Khadikar, PV Modelling of carbonic anhydrase inhibitory activity of sulfonamides using molecular negentropy. Bioorg Med Chem Lett13:447-53 (2003) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 4 |
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| Name: | Carbonic anhydrase 4 |
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| Synonyms: | CA-IV | CA4 | CAH4_BOVIN | Carbonate dehydratase IV | Carbonic Anhydrase IV | Carbonic anhydrase | Carbonic anhydrase 4 |
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| Type: | Enzyme |
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| Mol. Mass.: | 35152.74 |
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| Organism: | Bos taurus (bovine) |
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| Description: | Bovine isozyme, isolated from lung microsomes |
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| Residue: | 312 |
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| Sequence: | MRLLLALLVLAAAPPQARAASHWCYQIQVKPSNYTCLEPDEWEGSCQNNRQSPVNIVTAK
TQLDPNLGRFSFSGYNMKHQWVVQNNGHTVMVLLENKPSIAGGGLSTRYQATQLHLHWSR
AMDRGSEHSFDGERFAMEMHIVHEKEKGLSGNASQNQFAEDEIAVLAFMVEDGSKNVNFQ
PLVEALSDIPRPNMNTTMKEGVSLFDLLPEEESLRHYFRYLGSLTTPTCDEKVVWTVFQK
PIQLHRDQILAFSQKLFYDDQQKVNMTDNVRPVQSLGQRQVFRSGAPGLLLAQPLPTLLA
PVLACLTVGFLR
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| BDBM50079052 |
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| n/a |
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| Name | BDBM50079052 |
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| Synonyms: | 6-(5-Chloro-2,4-disulfamoyl-phenylcarbamoyl)-pyridine-2-carboxylic acid | CHEMBL328946 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H11ClN4O7S2 |
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| Mol. Mass. | 434.832 |
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| SMILES | NS(=O)(=O)c1cc(c(NC(=O)c2cccc(n2)C(O)=O)cc1Cl)S(N)(=O)=O |
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| Structure | 
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