| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic anhydrase 4 |
|---|
| Ligand | BDBM50079051 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_45434 (CHEMBL657034) |
|---|
| Ki | 40.0±n/a nM |
|---|
| Citation |  Agrawal, VK; Khadikar, PV Modelling of carbonic anhydrase inhibitory activity of sulfonamides using molecular negentropy. Bioorg Med Chem Lett13:447-53 (2003) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carbonic anhydrase 4 |
|---|
| Name: | Carbonic anhydrase 4 |
|---|
| Synonyms: | CA-IV | CA4 | CAH4_BOVIN | Carbonate dehydratase IV | Carbonic Anhydrase IV | Carbonic anhydrase | Carbonic anhydrase 4 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 35152.74 |
|---|
| Organism: | Bos taurus (bovine) |
|---|
| Description: | Bovine isozyme, isolated from lung microsomes |
|---|
| Residue: | 312 |
|---|
| Sequence: | MRLLLALLVLAAAPPQARAASHWCYQIQVKPSNYTCLEPDEWEGSCQNNRQSPVNIVTAK
TQLDPNLGRFSFSGYNMKHQWVVQNNGHTVMVLLENKPSIAGGGLSTRYQATQLHLHWSR
AMDRGSEHSFDGERFAMEMHIVHEKEKGLSGNASQNQFAEDEIAVLAFMVEDGSKNVNFQ
PLVEALSDIPRPNMNTTMKEGVSLFDLLPEEESLRHYFRYLGSLTTPTCDEKVVWTVFQK
PIQLHRDQILAFSQKLFYDDQQKVNMTDNVRPVQSLGQRQVFRSGAPGLLLAQPLPTLLA
PVLACLTVGFLR
|
|
|
|---|
| BDBM50079051 |
|---|
| n/a |
|---|
| Name | BDBM50079051 |
|---|
| Synonyms: | 6-[2-(4-Sulfamoyl-phenyl)-ethylcarbamoyl]-pyridine-2-carboxylic acid | CHEMBL88860 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H15N3O5S |
|---|
| Mol. Mass. | 349.362 |
|---|
| SMILES | NS(=O)(=O)c1ccc(CCNC(=O)c2cccc(n2)C(O)=O)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
