| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(2) dopamine receptor |
|---|
| Ligand | BDBM50223743 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_61144 (CHEMBL670681) |
|---|
| Ki | 437±n/a nM |
|---|
| Citation |  Caro, Y; Torrado, M; Masaguer, CF; Raviña, E; Padín, F; Brea, J; Loza, MI Chemoenzymatic synthesis and binding affinity of novel (R)- and (S)-3-aminomethyl-1-tetralones, potential atypical antipsychotics. Bioorg Med Chem Lett14:585-9 (2004) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(2) dopamine receptor |
|---|
| Name: | D(2) dopamine receptor |
|---|
| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 |
|---|
| Type: | Cell-surface receptors |
|---|
| Mol. Mass.: | 50647.10 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P14416 |
|---|
| Residue: | 443 |
|---|
| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
|
|
|
|---|
| BDBM50223743 |
|---|
| n/a |
|---|
| Name | BDBM50223743 |
|---|
| Synonyms: | CHEMBL421801 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H25FN2O3 |
|---|
| Mol. Mass. | 408.4653 |
|---|
| SMILES | COc1ccc2C(=O)CC(CN3CCC(CC3)c3noc4cc(F)ccc34)Cc2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
