| Reaction Details |
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 | Report a problem with these data |
| Target | Phosphatidylinositol 4-kinase type 2-alpha |
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| Ligand | BDBM50013721 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_152904 (CHEMBL758627) |
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| IC50 | 215300±n/a nM |
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| Citation |  Young, RC; Jones, M; Milliner, KJ; Rana, KK; Ward, JG Purine derivatives as competitive inhibitors of human erythrocyte membrane phosphatidylinositol 4-kinase. J Med Chem33:2073-80 (1990) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Phosphatidylinositol 4-kinase type 2-alpha |
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| Name: | Phosphatidylinositol 4-kinase type 2-alpha |
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| Synonyms: | P4K2A_HUMAN | PI4K2A | Phosphatidylinositol 4-kinase type 2-alpha | Phosphatidylinositol 4-kinase type II-alpha |
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| Type: | PROTEIN |
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| Mol. Mass.: | 54030.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_104812 |
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| Residue: | 479 |
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| Sequence: | MDETSPLVSPERAQPPDYTFPSGSGAHFPQVPGGAVRVAAAAGSGPSPPGSPGHDRERQP
LLDRARGAAAQGQTQTVAAQAQALAAQAAAAAHAAQAHRERNEFPEDPEFEAVVRQAELA
IERCIFPERIYQGSSGSYFVKDPQGRIIAVFKPKNEEPYGHLNPKWTKWLQKLCCPCCFG
RDCLVLNQGYLSEAGASLVDQKLELNIVPRTKVVYLASETFNYSAIDRVKSRGKRLALEK
VPKVGQRFNRIGLPPKVGSFQLFVEGYKDADYWLRRFEAEPLPENTNRQLLLQFERLVVL
DYIIRNTDRGNDNWLIKYDCPMDSSSSRDTDWVVVKEPVIKVAAIDNGLAFPLKHPDSWR
AYPFYWAWLPQAKVPFSQEIKDLILPKISDPNFVKDLEEDLYELFKKDPGFDRGQFHKQI
AVMRGQILNLTQALKDNKSPLHLVQMPPVIVETARSHQRSSSESYTQSFQSRKPFFSWW
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| BDBM50013721 |
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| n/a |
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| Name | BDBM50013721 |
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| Synonyms: | 8-Br-adenine | 8-Bromo-9H-purin-6-ylamine0.9M HCl | CHEMBL65747 |
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| Type | Small organic molecule |
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| Emp. Form. | C5H4BrN5 |
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| Mol. Mass. | 214.023 |
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| SMILES | Nc1ncnc2nc(Br)[nH]c12 |
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| Structure | 
|
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