Ki Summary

Reaction Details

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Target

cAMP-dependent protein kinase catalytic subunit gamma

Ligand

BDBM50228839

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_161405 (CHEMBL768314)

170±n/a nM

Citation

Ricouart, A; Gesquiere, JC; Tartar, A; Sergheraert, C Design of potent protein kinase inhibitors using the bisubstrate approach. J Med Chem34:73-8 (1991) [PubMed]

More Info.:

Get all data from this article, Assay Method

cAMP-dependent protein kinase catalytic subunit gamma

Name:

cAMP-dependent protein kinase catalytic subunit gamma

Synonyms:

KAPCG_HUMAN | PKA C-gamma | PRKACG | cAMP-dependent protein kinase (PKA) | cAMP-dependent protein kinase catalytic subunit gamma

Type:

PROTEIN

Mol. Mass.:

40442.03

Organism:

Homo sapiens (Human)

Description:

ChEMBL_104720

Residue:

351

Sequence:

MGNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVML
VRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLV
MEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGY
LQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFY
ADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFAT
TSWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF

BDBM50228839

n/a

Name

BDBM50228839

Synonyms:

CHEMBL415414

Type

Small organic molecule

Emp. Form.

C54H94N28O13S

Mol. Mass.

1375.569

SMILES

[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6])-[#7]S(=O)(=O)c1cccc2cnccc12)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](-[#8])=O

Structure