| Reaction Details |
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 | Report a problem with these data |
| Target | Translocator protein |
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| Ligand | BDBM50232188 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1646138 (CHEMBL3995194) |
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| Ki | 1.4±n/a nM |
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| Citation |  Cherukupalli, S; Karpoormath, R; Chandrasekaran, B; Hampannavar, GA; Thapliyal, N; Palakollu, VN An insight on synthetic and medicinal aspects of pyrazolo[1,5-a]pyrimidine scaffold. Eur J Med Chem126:298-352 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Translocator protein |
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| Name: | Translocator protein |
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| Synonyms: | Benzodiazepine receptors; peripheral & central | Bzrp | Mbr | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor (PBR) | Peripheral-Type Benzodiazepine Receptor | TSPO_RAT | Tspo |
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| Type: | Mitochondrion membrane protein |
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| Mol. Mass.: | 18945.84 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | Competitive binding experiments were performed on rat kidney mitochondrial membranes. |
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| Residue: | 169 |
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| Sequence: | MSQSWVPAVGLTLVPSLGGFMGAYFVRGEGLRWYASLQKPSWHPPRWTLAPIWGTLYSAM
GYGSYIIWKELGGFTEEAMVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLMLVSGVAT
ATTLAWHRVSPPAARLLYPYLAWLAFATMLNYYVWRDNSGRRGGSRLTE
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| BDBM50232188 |
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| n/a |
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| Name | BDBM50232188 |
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| Synonyms: | CHEMBL4070141 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H24ClN3O |
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| Mol. Mass. | 369.888 |
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| SMILES | CCC(CC)C(=O)Cc1c(nn2c(C)cc(C)nc12)-c1ccc(Cl)cc1 |
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| Structure | 
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