| Reaction Details |
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 | Report a problem with these data |
| Target | G-protein coupled receptor 39 |
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| Ligand | BDBM50232375 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1646463 (CHEMBL3995519) |
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| EC50 | 2.0±n/a nM |
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| Citation |  Frimurer, TM; Mende, F; Graae, AS; Engelstoft, MS; Egerod, KL; Nygaard, R; Gerlach, LO; Hansen, JB; Schwartz, TW; Holst, B Model-Based Discovery of Synthetic Agonists for the Zn J Med Chem60:886-898 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| G-protein coupled receptor 39 |
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| Name: | G-protein coupled receptor 39 |
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| Synonyms: | GPR39 | GPR39_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 51351.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_107977 |
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| Residue: | 453 |
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| Sequence: | MASPSLPGSDCSQIIDHSHVPEFEVATWIKITLILVYLIIFVMGLLGNSATIRVTQVLQK
KGYLQKEVTDHMVSLACSDILVFLIGMPMEFYSIIWNPLTTSSYTLSCKLHTFLFEACSY
ATLLHVLTLSFERYIAICHPFRYKAVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEYPL
VNVPSHRGLTCNRSSTRHHEQPETSNMSICTNLSSRWTVFQSSIFGAFVVYLVVLLSVAF
MCWNMMQVLMKSQKGSLAGGTRPPQLRKSESEESRTARRQTIIFLRLIVVTLAVCWMPNQ
IRRIMAAAKPKHDWTRSYFRAYMILLPFSETFFYLSSVINPLLYTVSSQQFRRVFVQVLC
CRLSLQHANHEKRLRVHAHSTTDSARFVQRPLLFASRRQSSARRTEKIFLSTFQSEAEPQ
SKSQSLSLESLEPNSGAKPANSAAENGFQEHEV
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| BDBM50232375 |
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| n/a |
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| Name | BDBM50232375 |
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| Synonyms: | CHEMBL4089047 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H21N7O3 |
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| Mol. Mass. | 419.4365 |
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| SMILES | COc1ccc(CCOC2CC(=O)Nc3c2c(C)nn3-c2ncnc3nc[nH]c23)cc1 |
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| Structure | 
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