| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic anhydrase 4 |
|---|
| Ligand | BDBM50234449 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1653006 (CHEMBL4002261) |
|---|
| Ki | 973±n/a nM |
|---|
| Citation |  Abdel-Aziz, AA; Angeli, A; El-Azab, AS; Abu El-Enin, MA; Supuran, CT Synthesis and biological evaluation of cyclic imides incorporating benzenesulfonamide moieties as carbonic anhydrase I, II, IV and IX inhibitors. Bioorg Med Chem25:1666-1671 (2017) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carbonic anhydrase 4 |
|---|
| Name: | Carbonic anhydrase 4 |
|---|
| Synonyms: | CA-IV | CA4 | CAH4_HUMAN | Carbonate dehydratase IV | Carbonic anhydrase | Carbonic anhydrase 4 (CA IV) | Carbonic anhydrase IV (CA IV) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 35037.98 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P22748 |
|---|
| Residue: | 312 |
|---|
| Sequence: | MRMLLALLALSAARPSASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTK
AKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSD
LPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGF
QPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFRE
PIQLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTVIKSGAPGRPLPWALPALLG
PMLACLLAGFLR
|
|
|
|---|
| BDBM50234449 |
|---|
| n/a |
|---|
| Name | BDBM50234449 |
|---|
| Synonyms: | CHEMBL4078596 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H18N2O4S |
|---|
| Mol. Mass. | 334.39 |
|---|
| SMILES | [H][C@@]12CC=CC[C@]1([H])C(=O)N(CCc1ccc(cc1)S(N)(=O)=O)C2=O |r,c:3| |
|---|
| Structure | 
|
|---|
Search and Browse
