| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-galactosidase |
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| Ligand | BDBM50236280 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1658945 (CHEMBL4008557) |
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| Ki | >100000±n/a nM |
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| Citation |  García-Moreno, MI; de la Mata, M; Sánchez-Fernández, EM; Benito, JM; Díaz-Quintana, A; Fustero, S; Nanba, E; Higaki, K; Sánchez-Alcázar, JA; García Fernández, JM; Ortiz Mellet, C Fluorinated Chaperone-ß-Cyclodextrin Formulations forß-Glucocerebrosidase Activity Enhancement in Neuronopathic Gaucher Disease. J Med Chem60:1829-1842 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-galactosidase |
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| Name: | Alpha-galactosidase |
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| Synonyms: | α-galactosidase | AGAL_COFAR | Alpha-galactosidase |
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| Type: | Protein |
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| Mol. Mass.: | 41306.82 |
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| Organism: | Coffea arabica (Coffee beans) |
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| Description: | n/a |
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| Residue: | 378 |
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| Sequence: | MVKSPGTEDYTRRSLLANGLGLTPPMGWNSWNHFRCNLDEKLIRETADAMVSKGLAALGY
KYINLDDCWAELNRDSQGNLVPKGSTFPSGIKALADYVHSKGLKLGIYSDAGTQTCSKTM
PGSLGHEEQDAKTFASWGVDYLKYDNCNNNNISPKERYPIMSKALLNSGRSIFFSLCEWG
EEDPATWAKEVGNSWRTTGDIDDSWSSMTSRADMNDKWASYAGPGGWNDPDMLEVGNGGM
TTTEYRSHFSIWALAKAPLLIGCDIRSMDGATFQLLSNAEVIAVNQDKLGVQGNKVKTYG
DLEVWAGPLSGKRVAVALWNRGSSTATITAYWSDVGLPSTAVVNARDLWAHSTEKSVKGQ
ISAAVDAHDSKMYVLTPQ
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| BDBM50236280 |
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| n/a |
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| Name | BDBM50236280 |
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| Synonyms: | CHEMBL4100971 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H24F13N3O5S |
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| Mol. Mass. | 665.466 |
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| SMILES | [H][C@@]12CO[C@@]([H])([C@H](O)[C@@H](O)[C@@H]1O)N2C(=S)NCCCCNC(=O)CCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F |r,TLB:7:6:2.3:12,THB:11:10:2.3:12| |
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| Structure | 
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