| Reaction Details |
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 | Report a problem with these data |
| Target | P2Y purinoceptor 12 |
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| Ligand | BDBM50237573 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1661643 (CHEMBL4011255) |
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| IC50 | 3590±n/a nM |
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| Citation |  Rafehi, M; Malik, EM; Neumann, A; Abdelrahman, A; Hanck, T; Namasivayam, V; Müller, CE; Baqi, Y Development of Potent and Selective Antagonists for the UTP-Activated P2Y J Med Chem60:3020-3038 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| P2Y purinoceptor 12 |
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| Name: | P2Y purinoceptor 12 |
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| Synonyms: | ADP-glucose receptor | ADPG-R | HORK3 | P2RY12 | P2T(AC) | P2Y purinoceptor 12 | P2Y(AC) | P2Y(ADP) | P2Y(cyc) | P2Y12 | P2Y12 platelet ADP receptor | P2Y12_HUMAN | Purinergic receptor P2Y12 | SP1999 |
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| Type: | Enzyme |
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| Mol. Mass.: | 39458.48 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9H244 |
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| Residue: | 342 |
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| Sequence: | MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFI
IFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITI
DRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKS
EFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFI
IIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFF
LCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM
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| BDBM50237573 |
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| n/a |
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| Name | BDBM50237573 |
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| Synonyms: | CHEMBL4090874 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H18N3NaO5S2 |
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| Mol. Mass. | 539.558 |
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| SMILES | [Na+].Nc1c(cc(Nc2ccc(SCc3cccnc3)cc2)c2C(=O)c3ccccc3C(=O)c12)S([O-])(=O)=O |
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| Structure | 
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