Citation | Aguilar, A; Lu, J; Liu, L; Du, D; Bernard, D; McEachern, D; Przybranowski, S; Li, X; Luo, R; Wen, B; Sun, D; Wang, H; Wen, J; Wang, G; Zhai, Y; Guo, M; Yang, D; Wang, S Discovery of 4-((3'R,4'S,5'R)-6¿-Chloro-4'-(3-chloro-2-fluorophenyl)-1'-ethyl-2¿-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3¿-indoline]-5'-carboxamido)bicyclo[2.2.2]octane-1-carboxylic Acid (AA-115/APG-115): A Potent and Orally Active Murine Double Minute 2 (MDM2) Inhibitor in Clinical Deve J Med Chem60:2819-2839 (2017) [PubMed] Article |
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