Reaction Details |
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Target | Interleukin-2 |
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Ligand | BDBM50238649 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEBML_1664050 |
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Kd | 8000±n/a nM |
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Citation | Quéméner, A; Maillasson, M; Arzel, L; Sicard, B; Vomiandry, R; Mortier, E; Dubreuil, D; Jacques, Y; Lebreton, J; Mathé-Allainmat, M Discovery of a Small-Molecule Inhibitor of Interleukin 15: Pharmacophore-Based Virtual Screening and Hit Optimization. J Med Chem60:6249-6272 (2017) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Interleukin-2 |
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Name: | Interleukin-2 |
Synonyms: | IL-2 | IL2 | IL2_HUMAN | INN=Aldesleukin | Interleukin-2 | Interleukin-2 (IL-2) | T-cell growth factor | TCGF |
Type: | Enzyme |
Mol. Mass.: | 17630.05 |
Organism: | Homo sapiens (Human) |
Description: | P60568 |
Residue: | 153 |
Sequence: | MYRMQLLSCIALSLALVTNSAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRML
TFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSE
TTFMCEYADETATIVEFLNRWITFCQSIISTLT
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BDBM50238649 |
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n/a |
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Name | BDBM50238649 |
Synonyms: | CHEMBL4103753 |
Type | Small organic molecule |
Emp. Form. | C27H30Cl2N6O2S |
Mol. Mass. | 573.537 |
SMILES | Cn1c(Cc2nn(C)c(=O)c3ccccc23)nnc1SCCCCCCCC(=O)Nc1ccc(Cl)cc1Cl |
Structure |
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