| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase 17B |
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| Ligand | BDBM50239011 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1664709 (CHEMBL4014505) |
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| IC50 | 1290±n/a nM |
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| Citation |  Wang, S; Xu, L; Lu, YT; Liu, YF; Han, B; Liu, T; Tang, J; Li, J; Wu, J; Li, JY; Yu, LF; Yang, F Discovery of benzofuran-3(2H)-one derivatives as novel DRAK2 inhibitors that protect islet?-cells from apoptosis. Eur J Med Chem130:195-208 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase 17B |
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| Name: | Serine/threonine-protein kinase 17B |
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| Synonyms: | DRAK2 | ST17B_HUMAN | STK17B | Serine/threonine-protein kinase 17B | Serine/threonine-protein kinase 17B (STK17B) |
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| Type: | Enzyme |
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| Mol. Mass.: | 42332.49 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O94768 |
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| Residue: | 372 |
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| Sequence: | MSRRRFDCRSISGLLTTTPQIPIKMENFNNFYILTSKELGRGKFAVVRQCISKSTGQEYA
AKFLKKRRRGQDCRAEILHEIAVLELAKSCPRVINLHEVYENTSEIILILEYAAGGEIFS
LCLPELAEMVSENDVIRLIKQILEGVYYLHQNNIVHLDLKPQNILLSSIYPLGDIKIVDF
GMSRKIGHACELREIMGTPEYLAPEILNYDPITTATDMWNIGIIAYMLLTHTSPFVGEDN
QETYLNISQVNVDYSEETFSSVSQLATDFIQSLLVKNPEKRPTAEICLSHSWLQQWDFEN
LFHPEETSSSSQTQDHSVRSSEDKTSKSSCNGTCGDREDKENIPEDSSMVSKRFRFDDSL
PNPHELVSDLLC
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| BDBM50239011 |
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| n/a |
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| Name | BDBM50239011 |
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| Synonyms: | CHEMBL4074827 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H16O5 |
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| Mol. Mass. | 312.3166 |
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| SMILES | CCOc1cc(\C=C2/Oc3c(cccc3OC)C2=O)ccc1O |
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| Structure | 
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