| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(4) dopamine receptor |
|---|
| Ligand | BDBM50102325 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 7.9±n/a nM |
|---|
| Comments | PDSP_1455 |
|---|
| Citation |  Roth, BL; Tandra, S; Burgess, LH; Sibley, DR; Meltzer, HY D4 dopamine receptor binding affinity does not distinguish between typical and atypical antipsychotic drugs. Psychopharmacology (Berl)120:365-8 (1995) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| D(4) dopamine receptor |
|---|
| Name: | D(4) dopamine receptor |
|---|
| Synonyms: | D(4) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.4 | DRD4_RAT | Dopamine receptor | Drd4 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 41307.65 |
|---|
| Organism: | RAT |
|---|
| Description: | DOPAMINE D4.4 0 RAT::P30729 |
|---|
| Residue: | 387 |
|---|
| Sequence: | MGNSSATGDGGLLAGRGPESLGTGTGLGGAGAAALVGGVLLIGMVLAGNSLVCVSVASER
ILQTPTNYFIVSLAAADLLLAVLVLPLFVYSEVQGGVWLLSPRLCDTLMAMDVMLCTASI
FNLCAISVDRFVAVTVPLRYNQQGQCQLLLIAATWLLSAAVAAPVVCGLNDVPGRDPTVC
CLEDRDYVVYSSICSFFLPCPLMLLLYWATFRGLRRWEAARHTKLHSRAPRRPSGPGPPV
SDPTQGPLFSDCPPPSPSLRTSPTVSSRPESDLSQSPCSPGCLLPDAALAQPPAPSSRRK
RGAKITGRERKAMRVLPVVVGAFLMCWTPFFVVHITRALCPACFVSPRLVSAVTWLGYVN
SALNPIIYTIFNAEFRSVFRKTLRLRC
|
|
|
|---|
| BDBM50102325 |
|---|
| n/a |
|---|
| Name | BDBM50102325 |
|---|
| Synonyms: | 6-(4-Methyl-piperazin-1-yl)-11H-dibenzo[b,e]azepine | CHEMBL340801 | Perlapine |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H21N3 |
|---|
| Mol. Mass. | 291.3901 |
|---|
| SMILES | CN1CCN(CC1)C1=Nc2ccccc2Cc2ccccc12 |t:8| |
|---|
| Structure | 
|
|---|
Search and Browse
