| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Glutamate receptor ionotropic, kainate 1 |
|---|
| Ligand | BDBM50289498 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 4100±n/a nM |
|---|
| Comments | PDSP_1293 |
|---|
| Citation |  Shimizu-Sasamata, M; Kawasaki-Yatsugi, S; Okada, M; Sakamoto, S; Yatsugi, S; Togami, J; Hatanaka, K; Ohmori, J; Koshiya, K; Usuda, S; Murase, K YM90K: pharmacological characterization as a selective and potent alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptor antagonist. J Pharmacol Exp Ther276:84-92 (1996) [PubMed] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Glutamate receptor ionotropic, kainate 1 |
|---|
| Name: | Glutamate receptor ionotropic, kainate 1 |
|---|
| Synonyms: | GRIK1_RAT | Glur5 | Glutamate receptor ionotropic kainate 1 | Glutamate receptor ionotropic, kainate | Glutamate receptor, ionotropic kainate 1 | Glutamate-Kainate | Grik1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 107860.82 |
|---|
| Organism: | RAT |
|---|
| Description: | P22756 |
|---|
| Residue: | 949 |
|---|
| Sequence: | MERSTVLIQPGLWTRDTSWTLLYFLCYILPQTSPQVLRIGGIFETVENEPVNVEELAFKF
AVTSINRNRTLMPNTTLTYDIQRINLFDSFEASRRACDQLALGVAALFGPSHSSSVSAVQ
SICNALEVPHIQTRWKHPSVDSRDLFYINLYPDYAAISRAVLDLVLYYNWKTVTVVYEDS
TGLIRLQELIKAPSRYNIKIKIRQLPPANKDAKPLLKEMKKSKEFYVIFDCSHETAAEIL
KQILFMGMMTEYYHYFFTTLDLFALDLELYRYSGVNMTGFRKLNIDNPHVSSIIEKWSME
RLQAPPRPETGLLDGMMTTEAALMYDAVYMVAIASHRASQLTVSSLQCHRHKPCALGPRF
MNLIKEARWDGLTGRITFNKTDGLRKDFDLDIISLKEEGTEKASGEVSKHLYKVWKKIGI
WNSNSGLNMTDGNRDRSNNITDSLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEAYCL
DLLKELSNILGFLYDVKLVPDGKYGAQNDKGEWNGMVKELIDHRADLAVAPLTITYVREK
VIDFSKPFMTLGISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFT
PYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTL
IIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVRDGSTMTFFKKSKISTYEKM
WAFMSSRQQSALVKNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYG
VGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEDSKEASALGVENIGGIFI
VLAAGLVLSVFVAIGEFLYKSRKNNDVEQKGKSSRLRFYFRNKVRFHGSKKESLGVEKCL
SFNAIMEELGISLKNQKKLKKKSRTKGKSSFTSILTCHQRRTQRKETVA
|
|
|
|---|
| BDBM50289498 |
|---|
| n/a |
|---|
| Name | BDBM50289498 |
|---|
| Synonyms: | 3-Hydroxy-6-nitro-7-sulfamoyl-benzo[f]quinoxalin-2-ol anion | NBQX |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H7N4O6S |
|---|
| Mol. Mass. | 335.273 |
|---|
| SMILES | NS(=O)(=O)c1cccc2c1c(cc1[n-]c(=[OH+])c(=O)[n-]c21)[N+]([O-])=O |
|---|
| Structure | 
|
|---|
Search and Browse
