| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 1D |
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| Ligand | BDBM84952 |
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| Substrate/Competitor | n/a |
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| Ki | 2511.89±n/a nM |
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| Comments | PDSP_3125 |
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| Citation |  Borsini, F; Giraldo, E; Monferini, E; Antonini, G; Parenti, M; Bietti, G; Donetti, A BIMT 17, a 5-HT2A receptor antagonist and 5-HT1A receptor full agonist in rat cerebral cortex. Naunyn Schmiedebergs Arch Pharmacol352:276-82 (1995) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| 5-hydroxytryptamine receptor 1D |
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| Name: | 5-hydroxytryptamine receptor 1D |
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| Synonyms: | 5-HT-1D | 5-HT1D | 5-hydroxytryptamine receptor 1D | 5HT1D_RAT | Htr1d | Serotonin 1 (5-HT1) receptor | Serotonin 1B/1D receptor | Serotonin receptor 1D |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41551.75 |
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| Organism: | RAT |
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| Description: | 5-HT1D HTR1D RAT::P28565 |
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| Residue: | 374 |
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| Sequence: | MSLPNQSLEGLPQEASNRSLNATGAWDPEVLQALRISLVVVLSIITLATVLSNAFVLTTI
LLTKKLHTPANYLIGSLATTDLLVSILVMPISIAYTTTRTWNFGQILCDIWVSSDITCCT
ASILHLCVIALDRYWAITDALEYSKRRTAGHAAAMIAAVWAISICISIPPLFWRQATAHE
EMSDCLVNTSQISYTIYSTCGAFYIPSILLIILYGRIYVAARSRILNPPSLYGKRFTTAQ
LITGSAGSSLCSLNPSLHESHTHTVGSPLFFNQVKIKLADSILERKRISAARERKATKTL
GIILGAFIICWLPFFVVSLVLPICRDSCWIHPALFDFFTWLGYLNSLINPVIYTVFNEDF
RQAFQRVVHFRKAS
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| BDBM84952 |
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| n/a |
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| Name | BDBM84952 |
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| Synonyms: | BIMT 17 | CAS_127941 | NSC_127941 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H21F3N4O |
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| Mol. Mass. | 390.4021 |
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| SMILES | FC(F)(F)c1ccc(cc1)N1CCN(CCn2c3ccccc3[nH]c2=O)CC1 |
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| Structure | 
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