| Reaction Details |
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 | Report a problem with these data |
| Target | Gamma-aminobutyric acid receptor subunit alpha-6 |
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| Ligand | BDBM50017309 |
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| Substrate/Competitor | n/a |
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| Ki | 227±n/a nM |
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| Comments | PDSP_821 |
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| Citation |  Hadingham, KL; Garrett, EM; Wafford, KA; Bain, C; Heavens, RP; Sirinathsinghji, DJ; Whiting, PJ Cloning of cDNAs encoding the human gamma-aminobutyric acid type A receptor alpha 6 subunit and characterization of the pharmacology of alpha 6-containing receptors. Mol Pharmacol49:253-9 (1996) [PubMed] |
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| More Info.: | Get all data from this article |
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| Gamma-aminobutyric acid receptor subunit alpha-6 |
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| Name: | Gamma-aminobutyric acid receptor subunit alpha-6 |
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| Synonyms: | GABA A alpha6 | GABA receptor alpha-6 subunit | GABRA6 | GBRA6_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 51029.60 |
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| Organism: | Homo sapiens (Human) |
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| Description: | GABA A alpha6 0 HUMAN::Q16445 |
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| Residue: | 453 |
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| Sequence: | MASSLPWLCIILWLENALGKLEVEGNFYSENVSRILDNLLEGYDNRLRPGFGGAVTEVKT
DIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLKFGGPTEILSLNNLMVSKIWTPDTFFRN
GKKSIAHNMTTPNKLFRIMQNGTILYTMRLTINADCPMRLVNFPMDGHACPLKFGSYAYP
KSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKSNTGEYVIMTVYFHLQRKM
GYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYA
TAMDWFIAVCFAFVFSALIEFAAVNYFTNLQTQKAKRKAQFAAPPTVTISKATEPLEAEI
VLHPDSKYHLKKRITSLSLPIVSSSEANKVLTRAPILQSTPVTPPPLSPAFGGTSKIDQY
SRILFPVAFAGFNLVYWVVYLSKDTMEVSSSVE
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| BDBM50017309 |
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| n/a |
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| Name | BDBM50017309 |
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| Synonyms: | 7-Chloro-3-(5-isopropyl-[1,2,4]oxadiazol-3-yl)-5-methyl-4,5-dihydro-2,5,10b-triaza-benzo[e]azulen-6-one | CHEMBL307202 | FG 8205 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H16ClN5O2 |
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| Mol. Mass. | 357.794 |
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| SMILES | CC(C)c1nc(no1)-c1ncn-2c1CN(C)C(=O)c1c(Cl)cccc-21 |
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| Structure | 
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