| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 4 |
|---|
| Ligand | BDBM85027 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 0.1±n/a nM |
|---|
| Comments | PDSP_1619 |
|---|
| Citation |  Hegde, SS; Eglen, RM Peripheral 5-HT4 receptors. FASEB J10:1398-407 (1996) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| 5-hydroxytryptamine receptor 4 |
|---|
| Name: | 5-hydroxytryptamine receptor 4 |
|---|
| Synonyms: | 5-HT4 | 5-hydroxytryptamine receptor 4 | 5HT4R_CAVPO | HTR4 | Serotonin 4 (5-HT4) receptor |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 43735.29 |
|---|
| Organism: | GUINEA PIG |
|---|
| Description: | 5-HT4 HTR4 GUINEA PIG::O70528 |
|---|
| Residue: | 388 |
|---|
| Sequence: | MDKLDANVSSKEGFGSVEKVVLLTFLSAVILMAILGNLLVMVAVCRDRQLRKIKTNYFIV
SLAFADLLVSVLVMPFGAIELVQDIWVYGEMFCLVRTSLDVLLTTASIFHLCCISLDRYY
AICCQPLVYRNKMTPLRIALMLGGCWVIPMFISFLPIMQGWNNIGIVDLIEKRKFNQNSN
STYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHARQIQVLQRAGAPAEGRP
QPADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQLWTAFLWL
GYINSGLNPFLYAFLNKSFRRAFLIILCCDDERYRRPSILGQTVPCSTTTINGSTHVLRD
TVECGGQWESQCHPAASSPLVAAQPIDT
|
|
|
|---|
| BDBM85027 |
|---|
| n/a |
|---|
| Name | BDBM85027 |
|---|
| Synonyms: | 1-(7-Chloro-8-amino-1,4-benzodioxane-5-yl)-3-[1-[3-(3,4-dimethoxyphenyl)propyl]piperidine-4-yl]propane-1-one | RS 100235 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C27H35ClN2O5 |
|---|
| Mol. Mass. | 503.03 |
|---|
| SMILES | COc1ccc(CCCN2CCC(CCC(=O)c3cc(Cl)c(N)c4OCCOc34)CC2)cc1OC |
|---|
| Structure | 
|
|---|
Search and Browse
