| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 7 |
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| Ligand | BDBM35255 |
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| Substrate/Competitor | n/a |
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| Ki | 10±n/a nM |
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| Comments | PDSP_2002 |
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| Citation |  Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding. Psychopharmacology (Berl)124:57-73 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| 5-hydroxytryptamine receptor 7 |
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| Name: | 5-hydroxytryptamine receptor 7 |
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| Synonyms: | 5-HT-7 | 5-HT-X | 5-HT7 | 5-hydroxytryptamine receptor 7 | 5-hydroxytryptamine receptor 7 (5HT7) | 5HT7 | 5HT7R_MOUSE | Htr7 | Serotonin 7 (5-HT7) receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 49932.71 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | P32304 |
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| Residue: | 448 |
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| Sequence: | MMDVNSSGRPDLYGHLRSLILPEVGRRLQDLSPDGGAHSVVSSWMPHLLSGFPEVTASPA
PTWDAPPDNVSGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSN
YLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVIS
IDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDF
GYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFSGFPRVQPESVISLNGVVKLQK
EVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTS
CSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHE
ALKLAERPERSEFVLQNCDHCGKKGHDT
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| BDBM35255 |
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| n/a |
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| Name | BDBM35255 |
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| Synonyms: | 2-Chlor-11-(2-dimethylaminoaethoxy)-dibenzo(b,f)-thiepin | 2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)thiepin | 2-[(8-chlorodibenzo[b,f]thiepin-10-yl)oxy]-N,N-dimethylethanamine | CHEMBL285802 | Nipolept | Zoleptil | zotepine |
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| Type | Small organic molecule |
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| Emp. Form. | C18H18ClNOS |
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| Mol. Mass. | 331.86 |
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| SMILES | CN(C)CCOC1=Cc2ccccc2Sc2ccc(Cl)cc12 |t:6| |
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| Structure | 
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