| Reaction Details |
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 | Report a problem with these data |
| Target | Protachykinin-1 |
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| Ligand | BDBM22869 |
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| Substrate/Competitor | n/a |
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| Ki | 1000±n/a nM |
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| Comments | PDSP_552 |
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| Citation |  Schotte, A; Janssen, PF; Gommeren, W; Luyten, WH; Van Gompel, P; Lesage, AS; De Loore, K; Leysen, JE Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding. Psychopharmacology (Berl)124:57-73 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| |
| Protachykinin-1 |
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| Name: | Protachykinin-1 |
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| Synonyms: | NKA | NKNA | Protachykinin-1 | Substance P | TAC1 | TAC2 | TKN1_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 15006.99 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Substance P 0 HUMAN::P20366 |
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| Residue: | 129 |
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| Sequence: | MKILVALAVFFLVSTQLFAEEIGANDDLNYWSDWYDSDQIKEELPEPFEHLLQRIARRPK
PQQFFGLMGKRDADSSIEKQVALLKALYGHGQISHKRHKTDSFVGLMGKRALNSVAYERS
AMQNYERRR
|
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| BDBM22869 |
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| n/a |
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| Name | BDBM22869 |
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| Synonyms: | 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene | CLOZARIL | Clozapine | Leponex | US10259786, Clozapine |
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| Type | Small organic molecule |
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| Emp. Form. | C18H19ClN4 |
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| Mol. Mass. | 326.823 |
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| SMILES | CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 |c:8,15| |
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| Structure | 
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