| Reaction Details |
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 | Report a problem with these data |
| Target | Gamma-aminobutyric acid receptor subunit alpha-4 |
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| Ligand | BDBM84956 |
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| Substrate/Competitor | n/a |
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| Ki | 6.8±n/a nM |
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| Comments | PDSP_503 |
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| Citation |  Gunnersen, D; Kaufman, CM; Skolnick, P Pharmacological properties of recombinant "diazepam-insensitive" GABAA receptors. Neuropharmacology35:1307-14 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Gamma-aminobutyric acid receptor subunit alpha-4 |
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| Name: | Gamma-aminobutyric acid receptor subunit alpha-4 |
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| Synonyms: | GBRA4_RAT | Gabra4 | Gamma-aminobutyric acid receptor (GABA(A)) subunit alpha-4 |
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| Type: | Enzyme |
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| Mol. Mass.: | 60972.37 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P28471 |
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| Residue: | 552 |
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| Sequence: | MVSVQKVPAIVLCSGVSLALLHVLCLATCLNESPGQNSKDEKLCPENFTRILDSLLDGYD
NRLRPGFGGPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWIDKRLKYDGPIEILRLN
NMMVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTISAECPMRLVDFP
MDGHACPLKFGSYAYPKSEMIYTWTKGPEKSVEVPKESSSLVQYDLIGQTVSSETIKSIT
GEYIVMTVYFHLRRKMGYFMIQTYIPCIMTVILSQVSFWINKESVPARTVFGITTVLTMT
TLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNIQMQKAKKKISKPPP
EVPAAPVLKEKHTETSLQNTHANLNMRKRTNALVHSESDVNSRTEVGNHSSKTTAAQESS
ETTPKAHLASSPNPFSRANAAETISAAARGLSSAASPSPHGTLQPAPLRSASARPAFGAR
LGRIKTTVNTTGVPGNVSATPPPSAPPPSGSGTSKIDKYARILFPVTFGAFNMVYWVVYL
SKDTMEKSESLM
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| BDBM84956 |
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| n/a |
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| Name | BDBM84956 |
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| Synonyms: | 2-(4-Methoxy-phenyl)-2,5-dihydro-pyrazolo[4,3-c]quinolin-3-one (CGS 9895) | CGS 9895 | CHEMBL296335 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H13N3O2 |
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| Mol. Mass. | 291.304 |
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| SMILES | COc1ccc(cc1)-n1[nH]c2c(cnc3ccccc23)c1=O |
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| Structure | 
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