| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50091032 |
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| Substrate/Competitor | n/a |
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| Ki | 59±n/a nM |
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| Comments | PDSP_2082 |
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| Citation |  Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH Dopamine D2-like sites in schizophrenia, but not in Alzheimer's, Huntington's, or control brains, for [3H]benzquinoline. Synapse25:137-46 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 50931.60 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P61169 |
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| Residue: | 444 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
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| BDBM50091032 |
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| n/a |
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| Name | BDBM50091032 |
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| Synonyms: | 6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl-ammonium(R(+)ADTN) | Aminotetralin-6,7-dihydroxy-(+) |
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| Type | Small organic molecule |
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| Emp. Form. | C10H14NO2 |
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| Mol. Mass. | 180.2231 |
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| SMILES | [NH3+][C@@H]1CCc2cc(O)c(O)cc2C1 |
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| Structure | 
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