| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM81774 |
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| Substrate/Competitor | n/a |
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| Ki | 1473±n/a nM |
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| Comments | PDSP_1785 |
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| Citation |  Seeman, P; Guan, HC; Nobrega, J; Jiwa, D; Markstein, R; Balk, JH; Picetti, R; Borrelli, E; Van Tol, HH Dopamine D2-like sites in schizophrenia, but not in Alzheimer's, Huntington's, or control brains, for [3H]benzquinoline. Synapse25:137-46 (1997) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DRD2_MOUSE | Dopamine D2 receptor | Dopamine Receptor D2 | Drd2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 50957.64 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | P61168 |
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| Residue: | 444 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKPDRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
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| BDBM81774 |
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| n/a |
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| Name | BDBM81774 |
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| Synonyms: | CAS_15676-16-1 | SULPIRIDE,(+) | Sulpiride-S | Sulpiride-l |
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| Type | n/a |
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| Emp. Form. | C15H23N3O4S |
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| Mol. Mass. | 341.426 |
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| SMILES | CCN1CCC[C@H]1CNC(=O)c1cc(ccc1OC)S(N)(=O)=O |r| |
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| Structure | 
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