| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2A |
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| Ligand | BDBM85067 |
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| Substrate/Competitor | n/a |
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| Ki | 5.8±n/a nM |
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| Comments | PDSP_1509 |
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| Citation |  Tang, AH; Franklin, SR; Himes, CS; Smith, MW; Tenbrink, RE PNU-96415E, a potential antipsychotic agent with clozapine-like pharmacological properties. J Pharmacol Exp Ther281:440-7 (1997) [PubMed] |
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| More Info.: | Get all data from this article |
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| 5-hydroxytryptamine receptor 2A |
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| Name: | 5-hydroxytryptamine receptor 2A |
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| Synonyms: | 5-HT-2A | 5-HT2 | 5-HT2A | 5-hydroxytryptamine receptor 2A (5-HT2A) | 5-hydroxytryptamine receptor 2A (5HT2A) | 5HT2A_RAT | Htr2 | Htr2a | Serotonin Receptor 2A |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 52852.05 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | Rat cortex membranes 5-HT2A receptors. |
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| Residue: | 471 |
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| Sequence: | MEILCEDNISLSSIPNSLMQLGDGPRLYHNDFNSRDANTSEASNWTIDAENRTNLSCEGY
LPPTCLSILHLQEKNWSALLTTVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIAD
MLLGFLVMPVSMLTILYGYRWPLPSKLCAIWIYLDVLFSTASIMHLCAISLDRYVAIQNP
IHHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDNFVLIGSF
VAFFIPLTIMVITYFLTIKSLQKEATLCVSDLSTRAKLASFSFLPQSSLSSEKLFQRSIH
REPGSYAGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNENVIGA
LLNVFVWIGYLSSAVNPLVYTLFNKTYRSAFSRYIQCQYKENRKPLQLILVNTIPALAYK
SSQLQVGQKKNSQEDAEQTVDDCSMVTLGKQQSEENCTDNIETVNEKVSCV
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| BDBM85067 |
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| n/a |
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| Name | BDBM85067 |
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| Synonyms: | CAS_170856-41-4 | CHEMBL81330 | PNU 96415E | PNU-96415E |
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| Type | Small organic molecule |
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| Emp. Form. | C21H25FN2O |
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| Mol. Mass. | 340.4344 |
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| SMILES | Fc1ccc(cc1)N1CCN(CCC2OCCc3ccccc23)CC1 |
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| Structure | 
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