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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | 5-hydroxytryptamine receptor 2C | ||
| Ligand | BDBM50000492 | ||
| Substrate/Competitor | n/a | ||
| Ki | 794.32±n/a nM | ||
| Comments | PDSP_1991 | ||
| Citation |  Bonhaus, DW; Weinhardt, KK; Taylor, M; DeSouza, A; McNeeley, PM; Szczepanski, K; Fontana, DJ; Trinh, J; Rocha, CL; Dawson, MW; Flippin, LA; Eglen, RM RS-102221: a novel high affinity and selective, 5-HT2C receptor antagonist. Neuropharmacology36:621-9 (1997) [PubMed] Article | ||
| More Info.: | Get all data from this article | ||
| 5-hydroxytryptamine receptor 2C | |||
| Name: | 5-hydroxytryptamine receptor 2C | ||
| Synonyms: | 5-HT-1C | 5-HT-2C | 5-HT1C | 5-HT2C | 5-HT2C-INI | 5-HT2c VGI | 5-HTR2C | 5-hydroxytryptamine receptor 1C | 5-hydroxytryptamine receptor 2C (5-HT-2C) | 5-hydroxytryptamine receptor 2C (5HT-2C) | 5HT-1C | 5HT2C_HUMAN | HTR1C | HTR2C | Serotonin (5-HT3) receptor | Serotonin 2c (5-HT2c) receptor | Serotonin Receptor 2C | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 51836.79 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P28335 | ||
| Residue: | 458 | ||
| Sequence: |
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| BDBM50000492 | |||
| n/a | |||
| Name | BDBM50000492 | ||
| Synonyms: | (zacopride)4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide | 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide | 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide (Zacopride) | 4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide(zacopride) | CHEMBL18041 | HTR5A4-Amino-N-(1-aza-bicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxy-benzamide | ZACOPRIDE | ZACOPRIDE,R | ZACOPRIDE,RS | ZACOPRIDE,S | ||
| Type | Small organic molecule | ||
| Emp. Form. | C15H20ClN3O2 | ||
| Mol. Mass. | 309.791 | ||
| SMILES | COc1cc(N)c(Cl)cc1C(=O)NC1CN2CCC1CC2 |(27.19,-33.96,;28.52,-34.73,;28.53,-36.27,;27.2,-37.04,;27.2,-38.58,;25.86,-39.35,;28.53,-39.36,;28.53,-40.89,;29.87,-38.58,;29.86,-37.03,;31.19,-36.26,;31.19,-34.72,;32.53,-37.02,;33.86,-36.25,;35.2,-37.02,;36.52,-36.25,;36.52,-34.71,;35.19,-33.94,;33.85,-34.71,;34.61,-36.04,;35.74,-34.91,)| | ||
| Structure | 
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