| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Homoserine kinase |
|---|
| Ligand | BDBM85124 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Enzyme Inhibition Assay |
|---|
| pH | 7.5±0 |
|---|
| Temperature | 310.15±0 K |
|---|
| Ki | 4.6e+2± 4e+1 nM |
|---|
| Citation |  De Pascale, G; Griffiths, EJ; Shakya, T; Nazi, I; Wright, GD Identification and characterization of new inhibitors of fungal homoserine kinase. Chembiochem12:1179-82 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Homoserine kinase |
|---|
| Name: | Homoserine kinase |
|---|
| Synonyms: | KHSE_ECOLI | thrB |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 33619.26 |
|---|
| Organism: | Escherichia coli |
|---|
| Description: | P00547 |
|---|
| Residue: | 310 |
|---|
| Sequence: | MVKVYAPASSANMSVGFDVLGAAVTPVDGALLGDVVTVEAAETFSLNNLGRFADKLPSEP
RENIVYQCWERFCQELGKQIPVAMTLEKNMPIGSGLGSSACSVVAALMAMNEHCGKPLND
TRLLALMGELEGRISGSIHYDNVAPCFLGGMQLMIEENDIISQQVPGFDEWLWVLAYPGI
KVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYSRQPELAAKLMKDVIAEPYRERLLP
GFRQARQAVAEIGAVASGISGSGPTLFALCDKPETAQRVADWLGKNYLQNQEGFVHICRL
DTAGARVLEN
|
|
|
|---|
| BDBM85124 |
|---|
| n/a |
|---|
| Name | BDBM85124 |
|---|
| Synonyms: | Thr1 inhibitor, 4 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H14O6 |
|---|
| Mol. Mass. | 338.3109 |
|---|
| SMILES | Oc1c(CC2C(=O)OC3C=CCC=C3C2=O)c(=O)oc2ccccc12 |c:9,12| |
|---|
| Structure | 
|
|---|
Search and Browse
