| Reaction Details |
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 | Report a problem with these data |
| Target | Gamma-aminobutyric acid receptor subunit alpha-3 |
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| Ligand | BDBM50032962 |
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| Substrate/Competitor | n/a |
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| Ki | 7700±n/a nM |
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| Comments | PDSP_3519 |
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| Citation |  Chebib, M; Vandenberg, RJ; Froestl, W; Johnston, GA Unsaturated phosphinic analogues of gamma-aminobutyric acid as GABA(C) receptor antagonists. Eur J Pharmacol329:223-9 (1997) [PubMed] |
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| More Info.: | Get all data from this article |
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| Gamma-aminobutyric acid receptor subunit alpha-3 |
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| Name: | Gamma-aminobutyric acid receptor subunit alpha-3 |
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| Synonyms: | GABA A Alpha3Beta3Gamma2 | GABA A receptor alpha-3/beta-2/gamma-2 | GABA C | GABA receptor alpha-3 subunit | GABA-A receptor | GABRA3 | GBRA3_HUMAN | Gamma-aminobutyric acid receptor subunit alpha-3 | agonist GABA site |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 55175.47 |
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| Organism: | Homo sapiens (Human) |
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| Description: | GABA A Alpha3Beta1Gamma2 0 HUMAN::P34903 |
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| Residue: | 492 |
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| Sequence: | MIITQTSHCYMTSLGILFLINILPGTTGQGESRRQEPGDFVKQDIGGLSPKHAPDIPDDS
TDNITIFTRILDRLLDGYDNRLRPGLGDAVTEVKTDIYVTSFGPVSDTDMEYTIDVFFRQ
TWHDERLKFDGPMKILPLNNLLASKIWTPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLL
YTMRLTIHAECPMHLEDFPMDVHACPLKFGSYAYTTAEVVYSWTLGKNKSVEVAQDGSRL
NQYDLLGHVVGTEIIRSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLN
RESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVN
YFTKRSWAWEGKKVPEALEMKKKTPAAPAKKTSTTFNIVGTTYPINLAKDTEFSTISKGA
APSASSTPTIIASPKATYVQDSPTETKTYNSVSKVDKISRIIFPVLFAIFNLVYWATYVN
RESAIKGMIRKQ
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| BDBM50032962 |
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| n/a |
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| Name | BDBM50032962 |
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| Synonyms: | ((Z)-3-Amino-propenyl)-phosphinic acid | CGP38593 | CGP70522 | CHEMBL113217 | CHEMBL324917 |
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| Type | Small organic molecule |
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| Emp. Form. | C3H8NO2P |
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| Mol. Mass. | 121.0749 |
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| SMILES | NCCCP(=O)=O |
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| Structure | 
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