Reaction Details | |||
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Target | Norepinephrine transporter | ||
Ligand | BDBM50020712 | ||
Substrate/Competitor | n/a | ||
Ki | 8.6±n/a nM | ||
Comments | PDSP_288 | ||
Citation | Owens, MJ; Morgan, WN; Plott, SJ; Nemeroff, CB Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J Pharmacol Exp Ther283:1305-22 (1997) [PubMed] | ||
More Info.: | Get all data from this article | ||
Norepinephrine transporter | |||
Name: | Norepinephrine transporter | ||
Synonyms: | n/a | ||
Type: | Enzyme Catalytic Domain | ||
Mol. Mass.: | 2082.45 | ||
Organism: | RAT | ||
Description: | Norepinephrine transporter 0 RAT::Q9JIA2 | ||
Residue: | 19 | ||
Sequence: |
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BDBM50020712 | |||
n/a | |||
Name | BDBM50020712 | ||
Synonyms: | 10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5H-dibenzo(a,d)cycloheptene | 10,11-dihydro-N,N-dimethyl-5H-dibenzo(a,d)heptalene-Delta(5),gamma-propylamine | 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine | 3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-amine | 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethylpropan-1-amine | 5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptatriene | 5-(3-dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene | 5-(gamma-dimethylaminopropylidene)-5H-dibenzo[a,d][1,4]cycloheptadiene | AMITRIPTYLINE | Amitriptylin | CHEMBL629 | ||
Type | Small organic molecule | ||
Emp. Form. | C20H23N | ||
Mol. Mass. | 277.4033 | ||
SMILES | [#6]-[#7](-[#6])-[#6]-[#6]\[#6]=[#6]-1/c2ccccc2-[#6]-[#6]-c2ccccc-12 | ||
Structure |