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Reaction Details
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TargetNorepinephrine transporter
LigandBDBM25870
Substrate/Competitorn/a
Ki 3042±n/a nM
CommentsPDSP_532
Citation Owens, MJMorgan, WNPlott, SJNemeroff, CB Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J Pharmacol Exp Ther283:1305-22 (1997) [PubMed]
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Norepinephrine transporter
Name:Norepinephrine transporter
Synonyms:n/a
Type:Enzyme Catalytic Domain
Mol. Mass.:2082.45
Organism:RAT
Description:Norepinephrine transporter 0 RAT::Q9JIA2
Residue:19
Sequence:
MLLARMKPQVQPELGGADQ
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BDBM25870
n/a
NameBDBM25870
Synonyms:1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile | CHEMBL549 | CITALOPRAM | CITALOPRAM HYDROBROMIDE | Escitalopram | [3H]Citalopram | [3H]Cytalopram | [3H]Escitalopram | [3H]Lexapro
Typeradiolabeled ligand
Emp. Form.C20H21FN2O
Mol. Mass.324.3919
SMILESCN(C)CCCC1(OCc2cc(ccc12)C#N)c1ccc(F)cc1
Structure
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