Reaction Details |
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Target | Norepinephrine transporter |
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Ligand | BDBM25870 |
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Substrate/Competitor | n/a |
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Ki | 3042±n/a nM |
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Comments | PDSP_532 |
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Citation | Owens, MJ; Morgan, WN; Plott, SJ; Nemeroff, CB Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J Pharmacol Exp Ther283:1305-22 (1997) [PubMed] |
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More Info.: | Get all data from this article |
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Norepinephrine transporter |
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Name: | Norepinephrine transporter |
Synonyms: | n/a |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 2082.45 |
Organism: | RAT |
Description: | Norepinephrine transporter 0 RAT::Q9JIA2 |
Residue: | 19 |
Sequence: | |
BDBM25870 |
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n/a |
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Name | BDBM25870 |
Synonyms: | 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile | CHEMBL549 | CITALOPRAM | CITALOPRAM HYDROBROMIDE | Escitalopram | [3H]Citalopram | [3H]Cytalopram | [3H]Escitalopram | [3H]Lexapro |
Type | radiolabeled ligand |
Emp. Form. | C20H21FN2O |
Mol. Mass. | 324.3919 |
SMILES | CN(C)CCCC1(OCc2cc(ccc12)C#N)c1ccc(F)cc1 |
Structure |
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