| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(4) dopamine receptor |
|---|
| Ligand | BDBM81486 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 2±n/a nM |
|---|
| Comments | PDSP_1249 |
|---|
| Citation |  Seeman, P; Tallerico, T Antipsychotic drugs which elicit little or no parkinsonism bind more loosely than dopamine to brain D2 receptors, yet occupy high levels of these receptors. Mol Psychiatry3:123-34 (1998) [PubMed] Article |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| D(4) dopamine receptor |
|---|
| Name: | D(4) dopamine receptor |
|---|
| Synonyms: | D(2C) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.2 | DOPAMINE D4.4 | DRD4 | DRD4_HUMAN | Dopamine D4 receptor |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 48373.19 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P21917 |
|---|
| Residue: | 419 |
|---|
| Sequence: | MGNRSTADADGLLAGRGPAAGASAGASAGLAGQGAAALVGGVLLIGAVLAGNSLVCVSVA
TERALQTPTNSFIVSLAAADLLLALLVLPLFVYSEVQGGAWLLSPRLCDALMAMDVMLCT
ASIFNLCAISVDRFVAVAVPLRYNRQGGSRRQLLLIGATWLLSAAVAAPVLCGLNDVRGR
DPAVCRLEDRDYVVYSSVCSFFLPCPLMLLLYWATFRGLQRWEVARRAKLHGRAPRRPSG
PGPPSPTPPAPRLPQDPCGPDCAPPAPGLPRGPCGPDCAPAAPSLPQDPCGPDCAPPAPG
LPPDPCGSNCAPPDAVRAAALPPQTPPQTRRRRRAKITGRERKAMRVLPVVVGAFLLCWT
PFFVVHITQALCPACSVPPRLVSAVTWLGYVNSALNPVIYTVFNAEFRNVFRKALRACC
|
|
|
|---|
| BDBM81486 |
|---|
| n/a |
|---|
| Name | BDBM81486 |
|---|
| Synonyms: | CAS_1050-79-9 | MOPERONE | NSC_4249 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H26FNO2 |
|---|
| Mol. Mass. | 355.4457 |
|---|
| SMILES | Cc1ccc(cc1)C1(O)CCN(CCCC(=O)c2ccc(F)cc2)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
