| Reaction Details |
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 | Report a problem with these data |
| Target | Collagenase 3 |
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| Ligand | BDBM85285 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorimetric Assay |
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| pH | 7±0 |
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| Temperature | 298.15±0 K |
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| IC50 | 158±n/a nM |
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| Citation |  Panico, AM; Vicini, P; Geronikaki, A; Incerti, M; Cardile, V; Crascì, L; Messina, R; Ronsisvalle, S Heteroarylimino-4-thiazolidinones as inhibitors of cartilage degradation. Bioorg Chem39:48-52 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Collagenase 3 |
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| Name: | Collagenase 3 |
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| Synonyms: | MMP-13 | MMP13 | MMP13_HUMAN | Matrix metalloproteinase-13 | Matrix metalloproteinase-13 (MMP-13) | Matrix metalloproteinase-13 (MMP13) |
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| Type: | Enzyme |
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| Mol. Mass.: | 53808.06 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P45452 |
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| Residue: | 471 |
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| Sequence: | MHPGVLAAFLFLSWTHCRALPLPSGGDEDDLSEEDLQFAERYLRSYYHPTNLAGILKENA
ASSMTERLREMQSFFGLEVTGKLDDNTLDVMKKPRCGVPDVGEYNVFPRTLKWSKMNLTY
RIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDG
PSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALM
FPIYTYTGKSHFMLPDDDVQGIQSLYGPGDEDPNPKHPKTPDKCDPSLSLDAITSLRGET
MIFKDRFFWRLHPQQVDAELFLTKSFWPELPNRIDAAYEHPSHDLIFIFRGRKFWALNGY
DILEGYPKKISELGLPKEVKKISAAVHFEDTGKTLLFSGNQVWRYDDTNHIMDKDYPRLI
EEDFPGIGDKVDAVYEKNGYIYFFNGPIQFEYSIWSNRIVRVMPANSILWC
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| BDBM85285 |
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| n/a |
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| Name | BDBM85285 |
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| Synonyms: | 2-(benzo[d]isothiazol-3-ylimino)-5-benzylidenethiazolidin-4-one, 3b |
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| Type | Small organic molecule |
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| Emp. Form. | C17H11N3O2S2 |
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| Mol. Mass. | 353.418 |
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| SMILES | Oc1ccc(\C=C2\S\C(NC2=O)=N/c2nsc3ccccc23)cc1 |
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| Structure | 
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