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TargetPTGFR
LigandBDBM50085910
Substrate/Competitorn/a
Ki 31±n/a nM
CommentsPDSP_547
Citation Sharif NAXu SXWilliams GWCrider JYGriffin BWDavis TL Pharmacology of [3H]prostaglandin E1/[3H]prostaglandin E2 and [3H]prostaglandin F2alpha binding to EP3 and FP prostaglandin receptor binding sites in bovine corpus luteum: characterization and correlation with functional data. J Pharmacol Exp Ther 286:1094-102 (1998) [PubMed]  Article
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PTGFR
Name:Prostanoid FP receptor
Synonyms:PGF receptor | PGF2 alpha receptor | ProstaglandinF2Alpha
Type:Enzyme Catalytic Domain
Mol. Mass.:41044.75
Organism:BOVINE
Description:ProstaglandinF2Alpha PTGFR BOVINE::P37289
Residue:362
Sequence:
MSTNSSIQPVSPESELLSNTTCQLEEDLSISFSIIFMTVGILSNSLAIAILMKAYQRFRQ
KYKSSFLLLASALVITDFFGHLINGTIAVFVYASDKDWIYFDKSNILCSIFGICMVFSGL
CPLFLGSLMAIERCIGVTKPIFHSTKITTKHVKMMLSGVCFFAVFVALLPILGHRDYKIQ
ASRTWCFYKTDEIKDWEDRFYLLLFAFLGLLALGISFVCNAITGISLLKVKFRSQQHRQG
RSHHFEMVIQLLGIMCVSCICWSPFLVTMASIGMNIQDFKDSCERTLFTLRMATWNQILD
PWVYILLRKAVLRNLYVCTRRCCGVHVISLHVWELSSIKDSLKVAAISDLPVTEKVTQQT
ST
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BDBM50085910
n/a
NameBDBM50085910
Synonyms:(Z)-7-{(1R,2R,3R,5S)-2-[(E)-(R)-4-(3-Chloro-phenoxy)-3-hydroxy-but-1-enyl]-3,5-dihydroxy-cyclopentyl}-hept-5-enoic acid | 7-{2-[4-(3-Chloro-phenoxy)-3-hydroxy-but-1-enyl]-3,5-dihydroxy-cyclopentyl}-hept-5-enoic acid | CHEMBL37853 | CLOPROSTENOL
TypeSmall organic molecule
Emp. Form.C22H29ClO6
Mol. Mass.424.915
SMILESO[C@@H](COc1cccc(Cl)c1)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O
Structure
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