| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor |
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| Ligand | BDBM50071173 |
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| Substrate/Competitor | n/a |
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| Ki | 10.71±n/a nM |
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| Comments | PDSP_933 |
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| Citation |  Chelala, JL; Kilani, A; Miller, MJ; Martin, RJ; Ernsberger, P Muscarinic receptor binding sites of the M4 subtype in porcine lung parenchyma. Pharmacol Toxicol83:200-7 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Muscarinic acetylcholine receptor |
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| Name: | Muscarinic acetylcholine receptor |
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| Synonyms: | CHRM4 | Cholinergic, muscarinic M4 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 50324.85 |
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| Organism: | PORCINE |
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| Description: | F1SIA0 |
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| Residue: | 479 |
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| Sequence: | MANVTPVNGSAGNQSVRLVTATHNRYETVEMVFIATVTGSLSLVTVVGNILVMLSIKVNR
QLQTVNNYFLFSLACADLIIGAFSMNLYTVYIIKGYWPLGAVVCDLWLALDYVVSNASVM
NLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTVP
DNQCFIQFLSNPAVTFGTAIAAFYLPVVIMTVLYVHISLASRSRVHKHRPEGPKEKKAKP
LAFLKSPLMKQSVKKPPPGEAAARGELRNGKLEEAPPPVLPPPPRPVADKDTSNESSSGS
ATQNTKERPPTELSTTEATTPAAPAPPLQPRTLNPASKWSKIQIVTKQTGNECVTAIEIV
PATPAGMRPAANVARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTWTPYNVMV
LVNTFCQSCIPDTVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYRNIGTAR
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| BDBM50071173 |
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| n/a |
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| Name | BDBM50071173 |
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| Synonyms: | (3R,4R,4aS,8aR)-4-[(E)-2-((2S,6S)-1,6-Dimethyl-piperidin-2-yl)-vinyl]-3-methyl-decahydro-naphtho[2,3-c]furan-1-one | CHEMBL59421 | HIMBACINE |
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| Type | Small organic molecule |
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| Emp. Form. | C22H35NO2 |
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| Mol. Mass. | 345.5188 |
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| SMILES | C[C@H]1OC(=O)C2C[C@H]3CCCC[C@@H]3[C@@H](\C=C\[C@@H]3CCC[C@H](C)N3C)C12 |
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| Structure | 
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