| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2C |
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| Ligand | BDBM22869 |
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| Substrate/Competitor | n/a |
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| Ki | 37±n/a nM |
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| Comments | PDSP_552 |
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| Citation |  Herrick-Davis, K; Grinde, E; Gauthier, C; Teitler, M Pharmacological characterization of the constitutively activated state of the serotonin 5-HT2C receptor. Ann N Y Acad Sci861:140-5 (1998) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| 5-hydroxytryptamine receptor 2C |
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| Name: | 5-hydroxytryptamine receptor 2C |
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| Synonyms: | 5-HT2C | 5-hydroxytryptamine receptor 2C | 5-hydroxytryptamine receptor 2C (5HT2c) | 5HT2C_RAT | 5ht1c | Htr1c | Htr2c | Serotonin (5-HT) receptor | Serotonin receptor 2a and 2c (5HT2A and 5HT2C) |
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| Type: | Enzyme |
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| Mol. Mass.: | 51935.10 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P08909 |
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| Residue: | 460 |
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| Sequence: | MVNLGNAVRSLLMHLIGLLVWQFDISISPVAAIVTDTFNSSDGGRLFQFPDGVQNWPALS
IVVIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYV
WPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVW
AISIGVSVPIPVIGLRDESKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYFLTIY
VLRRQTLMLLRGHTEEELANMSLNFLNCCCKKNGGEEENAPNPNPDQKPRRKKKEKRPRG
TMQAINNEKKASKVLGIVFFVFLIMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGY
VCSGINPLVYTLFNKIYRRAFSKYLRCDYKPDKKPPVRQIPRVAATALSGRELNVNIYRH
TNERVARKANDPEPGIEMQVENLELPVNPSNVVSERISSV
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| BDBM22869 |
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| n/a |
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| Name | BDBM22869 |
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| Synonyms: | 6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatricyclo[9.4.0.0^{3,8}]pentadeca-1,3(8),4,6,10,12,14-heptaene | CLOZARIL | Clozapine | Leponex | US10259786, Clozapine |
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| Type | Small organic molecule |
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| Emp. Form. | C18H19ClN4 |
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| Mol. Mass. | 326.823 |
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| SMILES | CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 |c:8,15| |
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| Structure | 
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