| Reaction Details |
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 | Report a problem with these data |
| Target | Corticotropin-releasing factor receptor 2 |
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| Ligand | BDBM85397 |
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| Substrate/Competitor | n/a |
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| Ki | >10000±n/a nM |
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| Comments | PDSP_586 |
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| Citation |  Okuyama, S; Chaki, S; Kawashima, N; Suzuki, Y; Ogawa, S; Nakazato, A; Kumagai, T; Okubo, T; Tomisawa, K Receptor binding, behavioral, and electrophysiological profiles of nonpeptide corticotropin-releasing factor subtype 1 receptor antagonists CRA1000 and CRA1001. J Pharmacol Exp Ther289:926-35 (1999) [PubMed] |
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| More Info.: | Get all data from this article |
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| Corticotropin-releasing factor receptor 2 |
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| Name: | Corticotropin-releasing factor receptor 2 |
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| Synonyms: | CRF-R-2 | CRF-R2 | CRF2 Beta | CRFR-2 | CRFR2_RAT | CRH-R-2 | CRH-R2 | Corticotropin releasing factor receptor | Corticotropin-releasing factor receptor 2 | Corticotropin-releasing hormone receptor 2 | Crf2r | Crhr2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 47697.09 |
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| Organism: | RAT |
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| Description: | CRF2 Beta 0 RAT::P47866 |
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| Residue: | 411 |
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| Sequence: | MDAALLLSLLEANCSLALAEELLLDGWGEPPDPEGPYSYCNTTLDQIGTCWPQSAPGALV
ERPCPEYFNGIKYNTTRNAYRECLENGTWASRVNYSHCEPILDDKQRKYDLHYRIALIIN
YLGHCVSVVALVAAFLLFLVLRSIRCLRNVIHWNLITTFILRNITWFLLQLIDHEVHEGN
EVWCRCVTTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTEHLRKWLFLFIGWCIPCPIIV
AWAVGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTS
ETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIVFIYFNSFLQSFQGFFVSVFYC
FFNGEVRSALRKRWHRWQDHHALRVPVARAMSIPTSPTRISFHSIKQTAAV
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| BDBM85397 |
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| n/a |
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| Name | BDBM85397 |
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| Synonyms: | CRA1000 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H35FN4S |
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| Mol. Mass. | 490.678 |
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| SMILES | CCN(c1nc(C)cc(n1)N1CCC=C(C1)c1cccc(F)c1)c1ccc(CC(C)C)cc1SC |c:14| |
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| Structure | 
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