| Reaction Details |
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 | Report a problem with these data |
| Target | 17-beta-hydroxysteroid dehydrogenase type 3 |
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| Ligand | BDBM71545 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| pH | 7.45±0 |
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| Temperature | 310.15±0 K |
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| IC50 | 7.62e+4±n/a nM |
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| Citation |  Le Lain, R; Nicholls, PJ; Smith, HJ; Maharlouie, FH Inhibitors of human and rat testes microsomal 17beta-hydroxysteroid dehydrogenase (17beta-HSD) as potential agents for prostatic cancer. J Enzym Inhib16:35-45 (2001) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| 17-beta-hydroxysteroid dehydrogenase type 3 |
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| Name: | 17-beta-hydroxysteroid dehydrogenase type 3 |
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| Synonyms: | 17-beta-hydroxysteroid dehydrogenase type 3 | DHB3_HUMAN | EDH17B3 | Estradiol 17-beta-dehydrogenase 3 | HSD17B3 | SDR12C2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 34525.39 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P37058 |
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| Residue: | 310 |
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| Sequence: | MGDVLEQFFILTGLLVCLACLAKCVRFSRCVLLNYWKVLPKSFLRSMGQWAVITGAGDGI
GKAYSFELAKRGLNVVLISRTLEKLEAIATEIERTTGRSVKIIQADFTKDDIYEHIKEKL
AGLEIGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVKMTQLILKHMESRQKGLI
LNISSGIALFPWPLYSMYSASKAFVCAFSKALQEEYKAKEVIIQVLTPYAVSTAMTKYLN
TNVITKTADEFVKESLNYVTIGGETCGCLAHEILAGFLSLIPAWAFYSGAFQRLLLTHYV
AYLKLNTKVR
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| BDBM71545 |
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| n/a |
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| Name | BDBM71545 |
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| Synonyms: | 2-[4-[(Z)-2-chloranyl-1,2-diphenyl-ethenyl]phenoxy]-N,N-diethyl-ethanamine;2-oxidanylpropane-1,2,3-tricarboxylic acid | 2-[4-[(Z)-2-chloro-1,2-diphenyl-vinyl]phenoxy]ethyl-diethyl-amine;citric acid | 2-[4-[(Z)-2-chloro-1,2-diphenylethenyl]phenoxy]-N,N-diethylethanamine;2-hydroxypropane-1,2,3-tricarboxylic acid | CHEMBL167779 | Clomiphene citrate salt | Clomiphene, 2 | MLS001332630 | SMR000875221 | cid_3033832 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H28ClNO |
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| Mol. Mass. | 405.96 |
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| SMILES | CCN(CC)CCOc1ccc(cc1)C(=C(/Cl)c1ccccc1)\c1ccccc1 |
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| Structure | 
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