| Reaction Details |
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 | Report a problem with these data |
| Target | Proteinase-activated receptor 2 |
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| Ligand | BDBM85518 |
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| Substrate/Competitor | n/a |
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| Ki | 260±n/a nM |
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| Comments | PDSP_1793 |
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| Citation |  Al-Ani, B; Saifeddine, M; Kawabata, A; Renaux, B; Mokashi, S; Hollenberg, MD Proteinase-activated receptor 2 (PAR(2)): development of a ligand-binding assay correlating with activation of PAR(2) by PAR(1)- and PAR(2)-derived peptide ligands. J Pharmacol Exp Ther290:753-60 (1999) [PubMed] |
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| More Info.: | Get all data from this article |
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| Proteinase-activated receptor 2 |
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| Name: | Proteinase-activated receptor 2 |
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| Synonyms: | F2rl1 | PAR2_RAT | Par2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44466.34 |
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| Organism: | RAT |
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| Description: | PAR2 F2RL1 RAT::Q63645 |
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| Residue: | 397 |
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| Sequence: | MRSLSLAWLLGGITLLAASASCNRTVNAPGPNSKGRSLIGRLDTPPPITGKGAPVEPGFS
VDEFSASVLTGKLTTVFLPVIYIIVFVIGLPSNGMALWVFFFRTKKKHPAVIYMANLALA
DLLSVIWFPLKISYHLHGNDWTYGDALCKVLIGFFYGNMYCSILFMTCLSVQRYWVIVNP
MGHSRKRANIAVGVSLAIWLLIFLVTIPLYVMRQTIYIPALNITTCHDVLPEEVLVGDMF
SYFLSLAIGVFLFPALLTASAYVLMIKTLRSSAMDEHSEKKRRRAIRLIITVLSMYFICF
APSNVLLVVHYFLIKSQRQSHVYALYLVALCLSTLNSCIDPFVYYFVSKDFRDQARNALL
CRSVRTVKRMQISLTSNKFSRKSSSYSSSSTSVKTSY
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| BDBM85518 |
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| n/a |
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| Name | BDBM85518 |
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| Synonyms: | tc-NH2 | trans-cinnamoyl-LIGRLO-NH2 |
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| Type | Small organic molecule |
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| Emp. Form. | C40H67N11O7 |
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| Mol. Mass. | 814.0295 |
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| SMILES | CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)C=Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN)C(N)=O |r,w:16.15| |
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| Structure | 
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