| Reaction Details |
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 | Report a problem with these data |
| Target | Serotonin N-acetyltransferase |
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| Ligand | BDBM85590 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | AANAT Assay |
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| pH | 6.8±0 |
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| Temperature | 310.15±0 K |
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| IC50 | 3.9e+2± 1.6e+2 nM |
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| Citation |  Beaurain, N; Mésangeau, C; Chavatte, P; Ferry, G; Audinot, V; Boutin, JA; Delagrange, P; Bennejean, C; Yous, S Design, synthesis and in vitro evaluation of novel derivatives as serotonin N-acetyltransferase inhibitors. J Enzyme Inhib Med Chem17:409-14 (2002) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Serotonin N-acetyltransferase |
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| Name: | Serotonin N-acetyltransferase |
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| Synonyms: | AANAT | Aralkylamine N-acetyltransferase | SNAT | SNAT_HUMAN | Serotonin N-acetyltransferase (AANAT) |
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| Type: | Protein |
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| Mol. Mass.: | 23350.36 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q16613 |
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| Residue: | 207 |
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| Sequence: | MSTQSTHPLKPEAPRLPPGIPESPSCQRRHTLPASEFRCLTPEDAVSAFEIEREAFISVL
GVCPLYLDEIRHFLTLCPELSLGWFEEGCLVAFIIGSLWDKERLMQESLTLHRSGGHIAH
LHVLAVHRAFRQQGRGPILLWRYLHHLGSQPAVRRAALMCEDALVPFYERFSFHAVGPCA
ITVGSLTFMELHCSLRGHPFLRRNSGC
|
|
|
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| BDBM85590 |
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| n/a |
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| Name | BDBM85590 |
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| Synonyms: | AANAT Inhibitor, 8h |
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| Type | Small organic molecule |
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| Emp. Form. | C12H11BrFNOS |
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| Mol. Mass. | 316.189 |
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| SMILES | Fc1ccc2scc(CCNC(=O)CBr)c2c1 |
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| Structure | 
|
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