| Reaction Details |
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 | Report a problem with these data |
| Target | Proto-oncogene tyrosine-protein kinase Src |
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| Ligand | BDBM85634 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Tyrosine Kinase Assay |
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| Temperature | 310.15±0 K |
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| IC50 | 3.0618e+5±n/a nM |
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| Citation |  Olgen, S; Akaho, E; Nebioglu, D Evaluation of indole esters as inhibitors of p60(c-Src) receptor tyrosine kinase and investigation of the inhibition using receptor docking studies. J Enzyme Inhib Med Chem18:485-90 (2003) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Proto-oncogene tyrosine-protein kinase Src |
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| Name: | Proto-oncogene tyrosine-protein kinase Src |
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| Synonyms: | Proto-oncogene c-Src | SRC | SRC_CHICK | Tyrosine-protein kinase SRC | c-Src | p60-Src | p60c-src | pp60c-src |
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| Type: | Tyr protein kinase |
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| Mol. Mass.: | 60015.36 |
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| Organism: | Gallus gallus (Chicken) |
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| Description: | P00523 |
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| Residue: | 533 |
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| Sequence: | MGSSKSKPKDPSQRRRSLEPPDSTHHGGFPASQTPNKTAAPDTHRTPSRSFGTVATEPKL
FGGFNTSDTVTSPQRAGALAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWL
AHSLTTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNPENPRGTFLVRESETT
KGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKHADGLCHR
LTNVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPG
TMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGEMGKYLRL
PQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQ
GAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYR
MPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
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| BDBM85634 |
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| n/a |
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| Name | BDBM85634 |
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| Synonyms: | Indole ester derivative, 14 | Indole ester derivative, 16 | Indole ester derivative, 20 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H34N4O2 |
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| Mol. Mass. | 446.5845 |
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| SMILES | O=C(OCCN(N1CCCCC1)N1CCCCC1)c1cc2ccccc2n1-c1ccccc1 |
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| Structure | 
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