| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-2C adrenergic receptor |
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| Ligand | BDBM85783 |
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| Substrate/Competitor | n/a |
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| Ki | 1.6±n/a nM |
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| Comments | PDSP_4019 |
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| Citation |  Bylund, DB; Gerety, ME; Happe, HK; Murrin, LC A robust GTP-induced shift in alpha(2)-adrenoceptor agonist affinity in tissue sections from rat brain. J Neurosci Methods105:159-66 (2001) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Alpha-2C adrenergic receptor |
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| Name: | Alpha-2C adrenergic receptor |
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| Synonyms: | ADA2C_RAT | Adra2c | Adrenergic receptor alpha | Alpha-2C adrenergic receptor | adrenergic Alpha2 | adrenergic Alpha2C |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 49890.50 |
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| Organism: | RAT |
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| Description: | adrenergic Alpha2 0 RAT::P22086 |
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| Residue: | 458 |
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| Sequence: | MASPALAAALAAAAAEGPNGSDAGEWGSGGGANASGTDWGPPPGQYSAGAVAGLAAVVGF
LIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFG
QVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISA
VISFPPLVSFYRRPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLR
TRTLSEKRGPAGPDGASPTTENGLGKAAGENGHCAPPRTEVEPDESSAAERRRRRGALRR
GGRRREGAEGDTGSADGPGPGLAAEQGARTASRSPGPGGRLSRASSRSVEFFLSRRRRAR
SSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQLPEPLFKFFFW
IGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ
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| BDBM85783 |
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| n/a |
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| Name | BDBM85783 |
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| Synonyms: | Brimonidine GTP | CAS_59803-98-4 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H20N9O13P3 |
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| Mol. Mass. | 639.3038 |
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| SMILES | Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)Nc2ccc(cc2)N=[N+]=[N-])[C@@H](O)[C@H]1O |r| |
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| Structure | 
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