| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M3 |
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| Ligand | BDBM50176065 |
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| Substrate/Competitor | n/a |
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| Ki | 2.4±n/a nM |
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| Comments | PDSP_111 |
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| Citation |  Bockman, CS; Bradley, ME; Dang, HK; Zeng, W; Scofield, MA; Dowd, FJ Molecular and pharmacological characterization of muscarinic receptor subtypes in a rat parotid gland cell line: comparison with native parotid gland. J Pharmacol Exp Ther297:718-26 (2001) [PubMed] |
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| More Info.: | Get all data from this article |
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| Muscarinic acetylcholine receptor M3 |
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| Name: | Muscarinic acetylcholine receptor M3 |
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| Synonyms: | ACM3_RAT | Cholinergic, muscarinic M3 | Chrm-3 | Chrm3 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 66086.66 |
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| Organism: | RAT |
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| Description: | Cholinergic, muscarinic M3 CHRM3 RAT::P08483 |
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| Residue: | 589 |
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| Sequence: | MTLHSNSTTSPLFPNISSSWVHSPSEAGLPLGTVTQLGSYNISQETGNFSSNDTSSDPLG
GHTIWQVVFIAFLTGFLALVTIIGNILVIVAFKVNKQLKTVNNYFLLSLACADLIIGVIS
MNLFTTYIIMNRWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRT
TKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAFY
MPVTIMTILYWRIYKETEKRTKELAGLQASGTEAEAENFVHPTGSSRSCSSYELQQQGVK
RSSRRKYGRCHFWFTTKSWKPSAEQMDQDHSSSDSWNNNDAAASLENSASSDEEDIGSET
RAIYSIVLKLPGHSSILNSTKLPSSDNLQVSNEDLGTVDVERNAHKLQAQKSMGDGDNCQ
KDFTKLPIQLESAVDTGKTSDTNSSADKTTATLPLSFKEATLAKRFALKTRSQITKRKRM
SLIKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFCDSCIPKTYWNLGYWLCYINSTVNP
VCYALCNKTFRTTFKTLLLCQCDKRKRRKQQYQQRQSVIFHKRVPEQAL
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| BDBM50176065 |
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| n/a |
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| Name | BDBM50176065 |
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| Synonyms: | 4-DAMP | 4-Diphenylacetoxy-1,1-dimethyl-piperidinium; iodide | Acetic acid 4-[(4-acetoxy-phenyl)-pyridin-2-yl-methyl]-phenyl ester | CHEMBL168067 | CHEMBL76897 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H26NO2 |
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| Mol. Mass. | 324.4361 |
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| SMILES | C[N+]1(C)CCC(CC1)OC(=O)C(c1ccccc1)c1ccccc1 |
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| Structure | 
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