| Reaction Details |
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 | Report a problem with these data |
| Target | Sodium- and chloride-dependent glycine transporter 1 |
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| Ligand | BDBM50122872 |
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| Substrate/Competitor | n/a |
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| Ki | >10000±n/a nM |
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| Comments | PDSP_1544 |
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| Citation |  Briejer, MR; Bosmans, JP; Van Daele, P; Jurzak, M; Heylen, L; Leysen, JE; Prins, NH; Schuurkes, JA The in vitro pharmacological profile of prucalopride, a novel enterokinetic compound. Eur J Pharmacol423:71-83 (2001) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Sodium- and chloride-dependent glycine transporter 1 |
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| Name: | Sodium- and chloride-dependent glycine transporter 1 |
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| Synonyms: | GlyT-1 | GlyT1 | Glycine transporter 1 | SC6A9_RAT | Slc6a9 | Sodium- and chloride-dependent glycine transporter 1 | Solute carrier family 6 member 9 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 71066.17 |
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| Organism: | attus norvegicus (Rat) |
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| Description: | Glycine-1-transporter 0 HUMAN::P28572 |
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| Residue: | 638 |
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| Sequence: | MAVAHGPVATSSPEQNGAVPSEATKKDQNLTRGNWGNQIEFVLTSVGYAVGLGNVWRFPY
LCYRNGGGAFMFPYFIMLVFCGIPLFFMELSFGQFASQGCLGVWRISPMFKGVGYGMMVV
STYIGIYYNVVICIAFYYFFSSMTHVLPWAYCNNPWNTPDCAGVLDASNLTNGSRPTALS
GNLSHLFNYTLQRTSPSEEYWRLYVLKLSDDIGDFGEVRLPLLGCLGVSWVVVFLCLIRG
VKSSGKVVYFTATFPYVVLTILFVRGVTLEGAFTGIMYYLTPKWDKILEAKVWGDAASQI
FYSLGCAWGGLITMASYNKFHNNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGVD
VSRVADHGPGLAFVAYPEALTLLPISPLWSLLFFFMLILLGLGTQFCLLETLVTAIVDEV
GNEWILQKKTYVTLGVAVAGFLLGIPLTSQAGIYWLLLMDNYAASFSLVVISCIMCVSIM
YIYGHRNYFQDIQMMLGFPPPLFFQICWRFVSPTIIFFILIFTVIQYRPITYNHYQYPGW
AVAIGFLMALSSVICIPLYALFQLCRTDGDTLLQRLKNATKPSRDWGPALLEHRTGRYAP
TTTPSPEDGFEVQPLHPDKAQIPIVGSNGSSRLQDSRI
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| BDBM50122872 |
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| n/a |
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| Name | BDBM50122872 |
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| Synonyms: | 4-Amino-5-chloro-2,3-dihydro-benzofuran-7-carboxylic acid [1-(3-methoxy-propyl)-piperidin-4-yl]-amide | CHEMBL117287 | PRUCALOPRIDE | US9663465, prucalopride |
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| Type | Small organic molecule |
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| Emp. Form. | C18H26ClN3O3 |
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| Mol. Mass. | 367.87 |
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| SMILES | COCCCN1CCC(CC1)NC(=O)c1cc(Cl)c(N)c2CCOc12 |
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| Structure | 
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